BRD-A75817871_blebbistatin_MCF7_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-A75817871_blebbistatin_MCF7_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CTSH cathepsin H
DCBLD2 discoidin, CUB and LCCL domain containing 2
GSN gelsolin
MLPH melanophilin
MTCL1 microtubule crosslinking factor 1
PCP4 Purkinje cell protein 4
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
STOM stomatin
TTC3 tetratricopeptide repeat domain 3
VAT1 vesicle amine transport 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD40 CD40 molecule, TNF receptor superfamily member 5
CKLF chemokine-like factor
DCK deoxycytidine kinase
HES1 hes family bHLH transcription factor 1
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL17RB interleukin 17 receptor B
ISG15 ISG15 ubiquitin-like modifier
MEF2C myocyte enhancer factor 2C
MKNK1 MAP kinase interacting serine/threonine kinase 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPIC peptidylprolyl isomerase C (cyclophilin C)
PPIF peptidylprolyl isomerase F
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPINK1 serine peptidase inhibitor, Kazal type 1
TM4SF1 transmembrane 4 L six family member 1
TRDV3 T cell receptor delta variable 3