BRD-A75817871_blebbistatin_HCC515_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

28 genes differentially expressed following the BRD-A75817871_blebbistatin_HCC515_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANO1 anoctamin 1, calcium activated chloride channel
BTG1 B-cell translocation gene 1, anti-proliferative
CA12 carbonic anhydrase XII
DUSP6 dual specificity phosphatase 6
MUC1 mucin 1, cell surface associated
NOTCH2NL notch 2 N-terminal like
RAP1GAP RAP1 GTPase activating protein
S100A10 S100 calcium binding protein A10
SERINC5 serine incorporator 5
SPDEF SAM pointed domain containing ETS transcription factor
TIPARP TCDD-inducible poly(ADP-ribose) polymerase

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BIRC5 baculoviral IAP repeat containing 5
CCNA2 cyclin A2
CDC6 cell division cycle 6
CDK1 cyclin-dependent kinase 1
CENPA centromere protein A
COL4A1 collagen, type IV, alpha 1
COL4A2 collagen, type IV, alpha 2
GINS2 GINS complex subunit 2 (Psf2 homolog)
IGFBP3 insulin-like growth factor binding protein 3
KIF18B kinesin family member 18B
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCM10 minichromosome maintenance complex component 10
MT1M metallothionein 1M
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
SIK1 salt-inducible kinase 1