BRD-A75817871_blebbistatin_CL34_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

156 genes differentially expressed following the BRD-A75817871_blebbistatin_CL34_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
BEX1 brain expressed, X-linked 1
CALHM2 calcium homeostasis modulator 2
CCND2 cyclin D2
CCR2 chemokine (C-C motif) receptor 2
COL6A2 collagen, type VI, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
DACH1 dachshund family transcription factor 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
DIO1 deiodinase, iodothyronine, type I
FAM129A family with sequence similarity 129, member A
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLNC filamin C, gamma
HCAR3 hydroxycarboxylic acid receptor 3
HEBP2 heme binding protein 2
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HMGB3 high mobility group box 3
HOMER3 homer scaffolding protein 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KRT18 keratin 18, type I
KRT19 keratin 19, type I
LOC100286895 cell division cycle 27 homolog pseudogene
MEIS2 Meis homeobox 2
MGP matrix Gla protein
MMP12 matrix metallopeptidase 12
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NCAM1 neural cell adhesion molecule 1
NEBL nebulette
PAWR PRKC, apoptosis, WT1, regulator
PBX1 pre-B-cell leukemia homeobox 1
PDE8B phosphodiesterase 8B
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPAP2B phosphatidic acid phosphatase type 2B
PRTN3 proteinase 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RBP1 retinol binding protein 1, cellular
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RRBP1 ribosome binding protein 1
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SCD5 stearoyl-CoA desaturase 5
SFRP1 secreted frizzled-related protein 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SRGN serglycin
SRSF5 serine/arginine-rich splicing factor 5
STAR steroidogenic acute regulatory protein
TES testin LIM domain protein
TF transferrin
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM6SF1 transmembrane 6 superfamily member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPK1 thiamin pyrophosphokinase 1
WASF3 WAS protein family, member 3

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRE5 adhesion G protein-coupled receptor E5
AMD1 adenosylmethionine decarboxylase 1
ARMCX3 armadillo repeat containing, X-linked 3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BST2 bone marrow stromal cell antigen 2
BTG3 BTG family, member 3
C5ORF15 chromosome 5 open reading frame 15
C8ORF4 chromosome 8 open reading frame 4
CA12 carbonic anhydrase XII
CDK4 cyclin-dependent kinase 4
CDK6 cyclin-dependent kinase 6
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHPT1 choline phosphotransferase 1
CNIH4 cornichon family AMPA receptor auxiliary protein 4
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
CYFIP2 cytoplasmic FMR1 interacting protein 2
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42
DEGS1 delta(4)-desaturase, sphingolipid 1
DLD dihydrolipoamide dehydrogenase
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP2 dual specificity phosphatase 2
EBNA1BP2 EBNA1 binding protein 2
EGR3 early growth response 3
EIF5B eukaryotic translation initiation factor 5B
EPB41L2 erythrocyte membrane protein band 4.1-like 2
ERBB2 erb-b2 receptor tyrosine kinase 2
ETNK1 ethanolamine kinase 1
FAM134B family with sequence similarity 134, member B
FASTKD3 FAST kinase domains 3
GPRC5A G protein-coupled receptor, class C, group 5, member A
HEBP1 heme binding protein 1
HEXIM1 hexamethylene bis-acetamide inducible 1
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HN1 hematological and neurological expressed 1
HOXB6 homeobox B6
HOXD1 homeobox D1
HPRT1 hypoxanthine phosphoribosyltransferase 1
IFITM1 interferon induced transmembrane protein 1
IFRD2 interferon-related developmental regulator 2
IL18 interleukin 18
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
IPO7 importin 7
JAM3 junctional adhesion molecule 3
JMJD6 jumonji domain containing 6
KIF2C kinesin family member 2C
KLF10 Kruppel-like factor 10
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LAMB3 laminin, beta 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LUC7L3 LUC7-like 3 (S. cerevisiae)
LYPLA1 lysophospholipase I
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MOAP1 modulator of apoptosis 1
MPZL1 myelin protein zero-like 1
MRPL19 mitochondrial ribosomal protein L19
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NR4A2 nuclear receptor subfamily 4, group A, member 2
NVL nuclear VCP-like
OSBPL10 oxysterol binding protein-like 10
OXA1L oxidase (cytochrome c) assembly 1-like
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PALLD palladin, cytoskeletal associated protein
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLS1 plastin 1
PRPF4 pre-mRNA processing factor 4
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RAB40B RAB40B, member RAS oncogene family
RABGGTB Rab geranylgeranyltransferase, beta subunit
RPA1 replication protein A1, 70kDa
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SF1 splicing factor 1
SFN stratifin
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMS spermine synthase
SNAP23 synaptosomal-associated protein, 23kDa
SPATA20 spermatogenesis associated 20
STK26 serine/threonine protein kinase 26
SYBU syntabulin (syntaxin-interacting)
TERF2IP telomeric repeat binding factor 2, interacting protein
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TM2D3 TM2 domain containing 3
TMEM165 transmembrane protein 165
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast)
TOP2A topoisomerase (DNA) II alpha 170kDa
TSPAN3 tetraspanin 3
XBP1 X-box binding protein 1
ZMYM2 zinc finger, MYM-type 2