BRD-A75817871_blebbistatin_A549_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-A75817871_blebbistatin_A549_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CLIC3 chloride intracellular channel 3
CRIP1 cysteine-rich protein 1 (intestinal)
DDIT4 DNA-damage-inducible transcript 4
EPHA3 EPH receptor A3
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
HIST1H2AC histone cluster 1, H2ac
HOXC10 homeobox C10
HSPA1A heat shock 70kDa protein 1A
IFITM1 interferon induced transmembrane protein 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
MARCKSL1 MARCKS-like 1
MLPH melanophilin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
RBM47 RNA binding motif protein 47
RBPMS RNA binding protein with multiple splicing
SLIT2 slit homolog 2 (Drosophila)
SOX4 SRY (sex determining region Y)-box 4
TPD52L1 tumor protein D52-like 1
VCAN versican
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
CCL2 chemokine (C-C motif) ligand 2
CD59 CD59 molecule, complement regulatory protein
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CPE carboxypeptidase E
CTGF connective tissue growth factor
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FOSL1 FOS-like antigen 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IL7R interleukin 7 receptor
JUN jun proto-oncogene
KRT6B keratin 6B, type II
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MCL1 myeloid cell leukemia 1
MSMO1 methylsterol monooxygenase 1
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
OLFM4 olfactomedin 4
PDGFC platelet derived growth factor C
PDZK1IP1 PDZK1 interacting protein 1
PEA15 phosphoprotein enriched in astrocytes 15
PMP22 peripheral myelin protein 22
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
REG3A regenerating islet-derived 3 alpha
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SPINK1 serine peptidase inhibitor, Kazal type 1
TFRC transferrin receptor
TGFBI transforming growth factor, beta-induced, 68kDa
TWIST1 twist family bHLH transcription factor 1