BRD-A74134989_Structure possibly contains amino acid derivative which is not supported in current version!_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-A74134989_Structure possibly contains amino acid derivative which is not supported in current version!_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ABHD2 abhydrolase domain containing 2
ACTA2 actin, alpha 2, smooth muscle, aorta
BMP4 bone morphogenetic protein 4
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CD52 CD52 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DCN decorin
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DPYSL3 dihydropyrimidinase-like 3
DSG2 desmoglein 2
EMP2 epithelial membrane protein 2
FGFR2 fibroblast growth factor receptor 2
FOS FBJ murine osteosarcoma viral oncogene homolog
GATA3 GATA binding protein 3
GPNMB glycoprotein (transmembrane) nmb
GREB1 growth regulation by estrogen in breast cancer 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LRMP lymphoid-restricted membrane protein
LUM lumican
MAN1A1 mannosidase, alpha, class 1A, member 1
MYO1D myosin ID
PTGIS prostaglandin I2 (prostacyclin) synthase
QPCT glutaminyl-peptide cyclotransferase
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
S100A8 S100 calcium binding protein A8
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SPINK1 serine peptidase inhibitor, Kazal type 1
STS steroid sulfatase (microsomal), isozyme S
TCTN1 tectonic family member 1
TERT telomerase reverse transcriptase
TMSB15A thymosin beta 15a
TPPP3 tubulin polymerization-promoting protein family member 3
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VAMP8 vesicle-associated membrane protein 8

decreased expression

Symbol Name
AKAP11 A kinase (PRKA) anchor protein 11
ASPH aspartate beta-hydroxylase
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BMP2 bone morphogenetic protein 2
C6ORF62 chromosome 6 open reading frame 62
COL9A3 collagen, type IX, alpha 3
DLD dihydrolipoamide dehydrogenase
GPX1 glutathione peroxidase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KIAA0226L KIAA0226-like
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SYBU syntabulin (syntaxin-interacting)
TFPI2 tissue factor pathway inhibitor 2