BRD-A72180425_2-[(chloroacetyl)(4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-A72180425_2-[(chloroacetyl)(4-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD163 CD163 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CECR1 cat eye syndrome chromosome region, candidate 1
CSRP1 cysteine and glycine-rich protein 1
CTSS cathepsin S
CXCL8 chemokine (C-X-C motif) ligand 8
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FOXO3 forkhead box O3
FTH1 ferritin, heavy polypeptide 1
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GPX2 glutathione peroxidase 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
INSIG1 insulin induced gene 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
MAN1A1 mannosidase, alpha, class 1A, member 1
MFAP5 microfibrillar associated protein 5
NR4A2 nuclear receptor subfamily 4, group A, member 2
PIR pirin (iron-binding nuclear protein)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORBS1 sorbin and SH3 domain containing 1
TPM2 tropomyosin 2 (beta)
TXNRD1 thioredoxin reductase 1
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
B3GNT1
CD24 CD24 molecule
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DKK1 dickkopf WNT signaling pathway inhibitor 1
FABP7 fatty acid binding protein 7, brain
GLRX glutaredoxin (thioltransferase)
KRT7 keratin 7, type II
MME membrane metallo-endopeptidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEFL neurofilament, light polypeptide
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NPY neuropeptide Y
PDZK1IP1 PDZK1 interacting protein 1
SCGB2A2 secretoglobin, family 2A, member 2
SLPI secretory leukocyte peptidase inhibitor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10