BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_SW620_6.0_h_0.08_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

120 genes differentially expressed following the BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_SW620_6.0_h_0.08_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADAMDEC1 ADAM-like, decysin 1
ADM adrenomedullin
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF3 activating transcription factor 3
BEX4 brain expressed, X-linked 4
C10ORF10 chromosome 10 open reading frame 10
C6ORF62 chromosome 6 open reading frame 62
CA2 carbonic anhydrase II
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CD24 CD24 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CD52 CD52 molecule
CD83 CD83 molecule
CEP57 centrosomal protein 57kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CPE carboxypeptidase E
CSRP2 cysteine and glycine-rich protein 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL9 chemokine (C-X-C motif) ligand 9
CYCS cytochrome c, somatic
DLD dihydrolipoamide dehydrogenase
EGFR epidermal growth factor receptor
GBP1 guanylate binding protein 1, interferon-inducible
GEM GTP binding protein overexpressed in skeletal muscle
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HILPDA hypoxia inducible lipid droplet-associated
HIST2H2BE histone cluster 2, H2be
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT17 keratin 17, type I
LMO3 LIM domain only 3 (rhombotin-like 2)
LTB lymphotoxin beta (TNF superfamily, member 3)
LUM lumican
MMP10 matrix metallopeptidase 10
MYBPC1 myosin binding protein C, slow type
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDE4DIP phosphodiesterase 4D interacting protein
PEA15 phosphoprotein enriched in astrocytes 15
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRKCI protein kinase C, iota
PRNP prion protein
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTHLH parathyroid hormone-like hormone
PTN pleiotrophin
RCAN2 regulator of calcineurin 2
S100A13 S100 calcium binding protein A13
S100A8 S100 calcium binding protein A8
SDCBP syndecan binding protein (syntenin)
SEPP1 selenoprotein P, plasma, 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SOD2 superoxide dismutase 2, mitochondrial
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTSSA serine palmitoyltransferase, small subunit A
TFRC transferrin receptor
TUBB2A tubulin, beta 2A class IIa
UBE3C ubiquitin protein ligase E3C
UPP1 uridine phosphorylase 1
WBP5 WW domain binding protein 5
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF331 zinc finger protein 331
ZNF395 zinc finger protein 395

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
AGR2 anterior gradient 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
C1QTNF3 C1q and tumor necrosis factor related protein 3
CD99 CD99 molecule
CDC20 cell division cycle 20
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CES1 carboxylesterase 1
CIRBP cold inducible RNA binding protein
CLIC4 chloride intracellular channel 4
COL10A1 collagen, type X, alpha 1
COL4A2 collagen, type IV, alpha 2
CTGF connective tissue growth factor
CXCL8 chemokine (C-X-C motif) ligand 8
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR24 24-dehydrocholesterol reductase
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DNMBP dynamin binding protein
ESR1 estrogen receptor 1
FOLR1 folate receptor 1 (adult)
H1F0 H1 histone family, member 0
HIST1H2BG histone cluster 1, H2bg
IL6ST interleukin 6 signal transducer
INHBA inhibin, beta A
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIAA0485 uncharacterized LOC57235
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
LAMA4 laminin, alpha 4
LAMP5 lysosomal-associated membrane protein family, member 5
LTBP3 latent transforming growth factor beta binding protein 3
MGP matrix Gla protein
MKI67 marker of proliferation Ki-67
MYB v-myb avian myeloblastosis viral oncogene homolog
PDGFC platelet derived growth factor C
PDLIM5 PDZ and LIM domain 5
PLAC8 placenta-specific 8
PLK1 polo-like kinase 1
PRSS3 protease, serine, 3
RGS4 regulator of G-protein signaling 4
RPL36 ribosomal protein L36
SPTBN1 spectrin, beta, non-erythrocytic 1
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
THBS4 thrombospondin 4
TPX2 TPX2, microtubule-associated
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TXNIP thioredoxin interacting protein
UGCG UDP-glucose ceramide glucosyltransferase