BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_HT29_6.0_h_0.08_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-A71390734_4-Demethoxydaunorubicin hydrochloride (65)_HT29_6.0_h_0.08_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BIRC3 baculoviral IAP repeat containing 3
CD83 CD83 molecule
DUSP14 dual specificity phosphatase 14
HLA-B major histocompatibility complex, class I, B
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
ISG20 interferon stimulated exonuclease gene 20kDa
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
MAP2K3 mitogen-activated protein kinase kinase 3
PCP4 Purkinje cell protein 4
PLD3 phospholipase D family, member 3
PRAME preferentially expressed antigen in melanoma
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
AURKA aurora kinase A
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNF cyclin F
CDC20 cell division cycle 20
CDCA3 cell division cycle associated 3
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPF centromere protein F, 350/400kDa
CXCL12 chemokine (C-X-C motif) ligand 12
DACH1 dachshund family transcription factor 1
DEPDC1 DEP domain containing 1
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
ENG endoglin
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAM64A family with sequence similarity 64, member A
GPSM2 G-protein signaling modulator 2
GTSE1 G-2 and S-phase expressed 1
HIST1H2BG histone cluster 1, H2bg
HMMR hyaluronan-mediated motility receptor (RHAMM)
KIF20A kinesin family member 20A
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
LGALS4 lectin, galactoside-binding, soluble, 4
MKI67 marker of proliferation Ki-67
MMD monocyte to macrophage differentiation-associated
NDC80 NDC80 kinetochore complex component
NEK2 NIMA-related kinase 2
PLK1 polo-like kinase 1
PROM1 prominin 1
PRSS3 protease, serine, 3
PSRC1 proline/serine-rich coiled-coil 1
RAP1GAP RAP1 GTPase activating protein
RBP4 retinol binding protein 4, plasma
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
UBE2C ubiquitin-conjugating enzyme E2C
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble