BRD-A70155556_NP-001236_VCAP_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

95 genes differentially expressed following the BRD-A70155556_NP-001236_VCAP_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMIGO2 adhesion molecule with Ig-like domain 2
ARL4C ADP-ribosylation factor-like 4C
ARMCX1 armadillo repeat containing, X-linked 1
ATP10D ATPase, class V, type 10D
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD44 CD44 molecule (Indian blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CETN2 centrin, EF-hand protein, 2
CLIC4 chloride intracellular channel 4
CPM carboxypeptidase M
CRABP2 cellular retinoic acid binding protein 2
ELANE elastase, neutrophil expressed
ELOVL5 ELOVL fatty acid elongase 5
F11R F11 receptor
FHL1 four and a half LIM domains 1
FILIP1L filamin A interacting protein 1-like
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCLC glutamate-cysteine ligase, catalytic subunit
GLRX glutaredoxin (thioltransferase)
GPER1 G protein-coupled estrogen receptor 1
GREB1 growth regulation by estrogen in breast cancer 1
GYPC glycophorin C (Gerbich blood group)
HDAC9 histone deacetylase 9
HGD homogentisate 1,2-dioxygenase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IL13RA1 interleukin 13 receptor, alpha 1
INSIG1 insulin induced gene 1
KYNU kynureninase
LGMN legumain
LOC100505650 uncharacterized LOC100505650
MAN1A1 mannosidase, alpha, class 1A, member 1
MEIS2 Meis homeobox 2
MME membrane metallo-endopeptidase
MPO myeloperoxidase
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRTN3 proteinase 3
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SC5D sterol-C5-desaturase
SQLE squalene epoxidase
STC1 stanniocalcin 1
STS steroid sulfatase (microsomal), isozyme S
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VTCN1 V-set domain containing T cell activation inhibitor 1
YPEL5 yippee-like 5 (Drosophila)
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
AASDHPPT aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
ACAT1 acetyl-CoA acetyltransferase 1
AKAP7 A kinase (PRKA) anchor protein 7
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
BEX1 brain expressed, X-linked 1
CCDC85B coiled-coil domain containing 85B
CD320 CD320 molecule
CRYAB crystallin, alpha B
CXCL14 chemokine (C-X-C motif) ligand 14
DAPK1 death-associated protein kinase 1
DCK deoxycytidine kinase
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM216A family with sequence similarity 216, member A
FBXO11 F-box protein 11
FKBP11 FK506 binding protein 11, 19 kDa
GOLIM4 golgi integral membrane protein 4
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXC6 homeobox C6
IFITM2 interferon induced transmembrane protein 2
IGKV1-5 immunoglobulin kappa variable 1-5
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
KRT10 keratin 10, type I
KRT7 keratin 7, type II
LAGE3 L antigen family, member 3
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAB21L2 mab-21-like 2 (C. elegans)
MT1E metallothionein 1E
NGRN neugrin, neurite outgrowth associated
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLK1 polo-like kinase 1
PLS3 plastin 3
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B
RPA3 replication protein A3, 14kDa
SMCO4 single-pass membrane protein with coiled-coil domains 4
SPINK1 serine peptidase inhibitor, Kazal type 1
TFF3 trefoil factor 3 (intestinal)
TIPIN TIMELESS interacting protein
TSPAN13 tetraspanin 13
UBE2S ubiquitin-conjugating enzyme E2S
ZCCHC24 zinc finger, CCHC domain containing 24