BRD-A70155556_NP-001236_SW948_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-A70155556_NP-001236_SW948_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
BLNK B-cell linker
CAST calpastatin
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHN1 chimerin 1
CPA3 carboxypeptidase A3 (mast cell)
CRABP2 cellular retinoic acid binding protein 2
DSP desmoplakin
ENO2 enolase 2 (gamma, neuronal)
FADS1 fatty acid desaturase 1
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
ITM2C integral membrane protein 2C
KRT14 keratin 14, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
MB myoglobin
MEIS1 Meis homeobox 1
MSMB microseminoprotein, beta-
MSMO1 methylsterol monooxygenase 1
NSDHL NAD(P) dependent steroid dehydrogenase-like
PCP4 Purkinje cell protein 4
PDE4B phosphodiesterase 4B, cAMP-specific
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMEM41B transmembrane protein 41B
TNNT1 troponin T type 1 (skeletal, slow)
TPM4 tropomyosin 4
VTCN1 V-set domain containing T cell activation inhibitor 1

decreased expression

Symbol Name
AGR2 anterior gradient 2
AP2B1 adaptor-related protein complex 2, beta 1 subunit
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
CCL2 chemokine (C-C motif) ligand 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL2 chemokine (C-X-C motif) ligand 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FKBP11 FK506 binding protein 11, 19 kDa
FOLR1 folate receptor 1 (adult)
GSN gelsolin
HPRT1 hypoxanthine phosphoribosyltransferase 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
LAMP1 lysosomal-associated membrane protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MCOLN1 mucolipin 1
MET MET proto-oncogene, receptor tyrosine kinase
NOLC1 nucleolar and coiled-body phosphoprotein 1
NRCAM neuronal cell adhesion molecule
PRSS2 protease, serine, 2 (trypsin 2)
PTCH1 patched 1
RAD23B RAD23 homolog B (S. cerevisiae)
RPL36 ribosomal protein L36
SRSF5 serine/arginine-rich splicing factor 5
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TSPAN13 tetraspanin 13