BRD-A70155556_NP-001236_SW620_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

86 genes differentially expressed following the BRD-A70155556_NP-001236_SW620_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGTR1 angiotensin II receptor, type 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCND2 cyclin D2
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
DDIT4 DNA-damage-inducible transcript 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
FGG fibrinogen gamma chain
FNBP1L formin binding protein 1-like
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GULP1 GULP, engulfment adaptor PTB domain containing 1
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
ITM2A integral membrane protein 2A
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LUM lumican
MMP12 matrix metallopeptidase 12
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NPY1R neuropeptide Y receptor Y1
NRCAM neuronal cell adhesion molecule
NTS neurotensin
PDZK1IP1 PDZK1 interacting protein 1
PRAME preferentially expressed antigen in melanoma
PSAP prosaposin
PSAT1 phosphoserine aminotransferase 1
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
QPCT glutaminyl-peptide cyclotransferase
RHOB ras homolog family member B
SCN3A sodium channel, voltage gated, type III alpha subunit
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9
SLC38A2 solute carrier family 38, member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
STAR steroidogenic acute regulatory protein
TPD52L1 tumor protein D52-like 1
TRIB3 tribbles pseudokinase 3
TRIM2 tripartite motif containing 2
UBE2A ubiquitin-conjugating enzyme E2A
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AKR1C2 aldo-keto reductase family 1, member C2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BST2 bone marrow stromal cell antigen 2
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CDK6 cyclin-dependent kinase 6
CTSH cathepsin H
CXCL14 chemokine (C-X-C motif) ligand 14
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DUSP4 dual specificity phosphatase 4
EFNB2 ephrin-B2
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
FST follistatin
GYG1 glycogenin 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
KIF14 kinesin family member 14
KRT5 keratin 5, type II
NQO1 NAD(P)H dehydrogenase, quinone 1
PBX3 pre-B-cell leukemia homeobox 3
PER2 period circadian clock 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PPAT phosphoribosyl pyrophosphate amidotransferase
PROSC proline synthetase co-transcribed homolog (bacterial)
RBP4 retinol binding protein 4, plasma
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
S100A2 S100 calcium binding protein A2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SDC2 syndecan 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SET SET nuclear proto-oncogene
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SOX9 SRY (sex determining region Y)-box 9
SPATS2L spermatogenesis associated, serine-rich 2-like
TRPS1 trichorhinophalangeal syndrome I