BRD-A70155556_NP-001236_NCIH508_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

214 genes differentially expressed following the BRD-A70155556_NP-001236_NCIH508_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKT3 v-akt murine thymoma viral oncogene homolog 3
ALB albumin
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
BEX4 brain expressed, X-linked 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCK cholecystokinin
CCND2 cyclin D2
COL6A2 collagen, type VI, alpha 2
COLEC12 collectin sub-family member 12
CPA3 carboxypeptidase A3 (mast cell)
CXORF57 chromosome X open reading frame 57
DCN decorin
DHRS2 dehydrogenase/reductase (SDR family) member 2
DSP desmoplakin
DSTN destrin (actin depolymerizing factor)
E2F2 E2F transcription factor 2
FAP fibroblast activation protein, alpha
FBLN1 fibulin 1
FGFR3 fibroblast growth factor receptor 3
FHL1 four and a half LIM domains 1
FHOD3 formin homology 2 domain containing 3
FN1 fibronectin 1
GAS6 growth arrest-specific 6
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLDC glycine dehydrogenase (decarboxylating)
GYPC glycophorin C (Gerbich blood group)
H1FX H1 histone family, member X
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
KRT19 keratin 19, type I
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN2A1 mannosidase, alpha, class 2A, member 1
MEIS2 Meis homeobox 2
MFSD10 major facilitator superfamily domain containing 10
MPPED2 metallophosphoesterase domain containing 2
MXRA5 matrix-remodelling associated 5
NCAM1 neural cell adhesion molecule 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
PAWR PRKC, apoptosis, WT1, regulator
PBX1 pre-B-cell leukemia homeobox 1
PCDH17 protocadherin 17
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDIA3 protein disulfide isomerase family A, member 3
PDZK1IP1 PDZK1 interacting protein 1
PERP PERP, TP53 apoptosis effector
PFKL phosphofructokinase, liver
PHGDH phosphoglycerate dehydrogenase
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PXDN peroxidasin
RAB2A RAB2A, member RAS oncogene family
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RBP1 retinol binding protein 1, cellular
RCAN2 regulator of calcineurin 2
RHOBTB1 Rho-related BTB domain containing 1
SATB2 SATB homeobox 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
SRSF5 serine/arginine-rich splicing factor 5
SST somatostatin
SULF1 sulfatase 1
TCEAL2 transcription elongation factor A (SII)-like 2
TF transferrin
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THBS2 thrombospondin 2
TMSB15A thymosin beta 15a
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPM4 tropomyosin 4
TRO trophinin
WLS wntless Wnt ligand secretion mediator
XIST X inactive specific transcript (non-protein coding)
ZNF711 zinc finger protein 711
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACOT9 acyl-CoA thioesterase 9
ACTN1 actinin, alpha 1
ADGRE5 adhesion G protein-coupled receptor E5
ANXA3 annexin A3
AQP3 aquaporin 3 (Gill blood group)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
BAG1 BCL2-associated athanogene
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BIRC5 baculoviral IAP repeat containing 5
BST2 bone marrow stromal cell antigen 2
C8ORF33 chromosome 8 open reading frame 33
CALML4 calmodulin-like 4
CCND1 cyclin D1
CCND3 cyclin D3
CD59 CD59 molecule, complement regulatory protein
CDK4 cyclin-dependent kinase 4
CDKN3 cyclin-dependent kinase inhibitor 3
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHPT1 choline phosphotransferase 1
CNIH1 cornichon family AMPA receptor auxiliary protein 1
CP ceruloplasmin (ferroxidase)
CRYAB crystallin, alpha B
CYC1 cytochrome c-1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DARS aspartyl-tRNA synthetase
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLD dihydrolipoamide dehydrogenase
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF5 eukaryotic translation initiation factor 5
EIF5B eukaryotic translation initiation factor 5B
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
FAM13A family with sequence similarity 13, member A
FHL2 four and a half LIM domains 2
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLS glutaminase
GTF3A general transcription factor IIIA
GTPBP8 GTP-binding protein 8 (putative)
HBB hemoglobin, beta
HES1 hes family bHLH transcription factor 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPH1 heat shock 105kDa/110kDa protein 1
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IRAK1 interleukin-1 receptor-associated kinase 1
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
LAMB3 laminin, beta 3
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LRP10 low density lipoprotein receptor-related protein 10
LRRC16A leucine rich repeat containing 16A
LTF lactotransferrin
LUC7L3 LUC7-like 3 (S. cerevisiae)
LY75 lymphocyte antigen 75
MAB21L2 mab-21-like 2 (C. elegans)
MET MET proto-oncogene, receptor tyrosine kinase
MGLL monoglyceride lipase
MLEC malectin
MMP7 matrix metallopeptidase 7
MPZL1 myelin protein zero-like 1
MRPL19 mitochondrial ribosomal protein L19
MTDH metadherin
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIB nuclear factor I/B
NOLC1 nucleolar and coiled-body phosphoprotein 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PDZD8 PDZ domain containing 8
PIP prolactin-induced protein
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
PLAC8 placenta-specific 8
PLAGL1 pleiomorphic adenoma gene-like 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PPARG peroxisome proliferator-activated receptor gamma
PPIG peptidylprolyl isomerase G (cyclophilin G)
PROM1 prominin 1
PRPF4 pre-mRNA processing factor 4
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTDSS1 phosphatidylserine synthase 1
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PUF60 poly-U binding splicing factor 60KDa
RAB40B RAB40B, member RAS oncogene family
RBKS ribokinase
RCN1 reticulocalbin 1, EF-hand calcium binding domain
RPIA ribose 5-phosphate isomerase A
RPL36AL ribosomal protein L36a-like
RPL37A ribosomal protein L37a
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEH1L SEH1-like (S. cerevisiae)
SERBP1 SERPINE1 mRNA binding protein 1
SFN stratifin
SHB Src homology 2 domain containing adaptor protein B
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SPAG1 sperm associated antigen 1
SPRY2 sprouty homolog 2 (Drosophila)
SYBU syntabulin (syntaxin-interacting)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TMEM47 transmembrane protein 47
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAM1 translocation associated membrane protein 1
TSPAN3 tetraspanin 3
TSPAN31 tetraspanin 31
TSPAN8 tetraspanin 8
TUBB2B tubulin, beta 2B class IIb
UBAP2 ubiquitin associated protein 2
WDR3 WD repeat domain 3
WDR43 WD repeat domain 43
XBP1 X-box binding protein 1
ZNF330 zinc finger protein 330