BRD-A70155556_NP-001236_HT29_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-A70155556_NP-001236_HT29_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACAT2 acetyl-CoA acetyltransferase 2
ACKR3 atypical chemokine receptor 3
ACLY ATP citrate lyase
ADGRG1 adhesion G protein-coupled receptor G1
ALDOC aldolase C, fructose-bisphosphate
AMIGO2 adhesion molecule with Ig-like domain 2
ARG2 arginase 2
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARMCX1 armadillo repeat containing, X-linked 1
ASS1 argininosuccinate synthase 1
BEX4 brain expressed, X-linked 4
C10ORF10 chromosome 10 open reading frame 10
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CAST calpastatin
CD9 CD9 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CHGB chromogranin B
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DHCR24 24-dehydrocholesterol reductase
DHCR7 7-dehydrocholesterol reductase
EBP emopamil binding protein (sterol isomerase)
EFNB2 ephrin-B2
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FADS3 fatty acid desaturase 3
FASN fatty acid synthase
FDFT1 farnesyl-diphosphate farnesyltransferase 1
FDPS farnesyl diphosphate synthase
GAGE3 G antigen 3
GAS1 growth arrest-specific 1
GSTA1 glutathione S-transferase alpha 1
HLA-B major histocompatibility complex, class I, B
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDI1 isopentenyl-diphosphate delta isomerase 1
INHBA inhibin, beta A
INSIG1 insulin induced gene 1
IRS2 insulin receptor substrate 2
JUND jun D proto-oncogene
LDLR low density lipoprotein receptor
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MEOX2 mesenchyme homeobox 2
MGLL monoglyceride lipase
MSMO1 methylsterol monooxygenase 1
NPTX2 neuronal pentraxin II
NSDHL NAD(P) dependent steroid dehydrogenase-like
OSBPL10 oxysterol binding protein-like 10
PANK3 pantothenate kinase 3
PEG10 paternally expressed 10
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RCAN2 regulator of calcineurin 2
RGCC regulator of cell cycle
SC5D sterol-C5-desaturase
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SQLE squalene epoxidase
SREBF2 sterol regulatory element binding transcription factor 2
STXBP1 syntaxin binding protein 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM97 transmembrane protein 97
TRIB3 tribbles pseudokinase 3
TRIM13 tripartite motif containing 13
TUBB2A tubulin, beta 2A class IIa
VCAN versican
ZNF395 zinc finger protein 395
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
ANXA3 annexin A3
ARG1 arginase 1
CA2 carbonic anhydrase II
CDC42 cell division cycle 42
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYBA cytochrome b-245, alpha polypeptide
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EPCAM epithelial cell adhesion molecule
GPRC5A G protein-coupled receptor, class C, group 5, member A
RGS1 regulator of G-protein signaling 1
RGS10 regulator of G-protein signaling 10
SLPI secretory leukocyte peptidase inhibitor
SMC1A structural maintenance of chromosomes 1A
TSPAN4 tetraspanin 4
UBE2E1 ubiquitin-conjugating enzyme E2E 1
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28