BRD-A70155556_NP-001236_HCC515_24.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

120 genes differentially expressed following the BRD-A70155556_NP-001236_HCC515_24.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ANPEP alanyl (membrane) aminopeptidase
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ATXN1 ataxin 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
BTG2 BTG family, member 2
C6ORF62 chromosome 6 open reading frame 62
CA12 carbonic anhydrase XII
CA2 carbonic anhydrase II
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLCA2 chloride channel accessory 2
DMXL2 Dmx-like 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP3 fatty acid binding protein 3, muscle and heart
GREB1 growth regulation by estrogen in breast cancer 1
GSN gelsolin
HIST1H2AC histone cluster 1, H2ac
HSPA1A heat shock 70kDa protein 1A
HSPA4 heat shock 70kDa protein 4
JUN jun proto-oncogene
KIAA1033 KIAA1033
KLF6 Kruppel-like factor 6
LYZ lysozyme
MAN1A1 mannosidase, alpha, class 1A, member 1
MKNK2 MAP kinase interacting serine/threonine kinase 2
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MTSS1 metastasis suppressor 1
MUC1 mucin 1, cell surface associated
MVP major vault protein
NDRG1 N-myc downstream regulated 1
PLXNB2 plexin B2
PRUNE2 prune homolog 2 (Drosophila)
PSD3 pleckstrin and Sec7 domain containing 3
RHOA ras homolog family member A
RSRP1 arginine/serine-rich protein 1
S100A14 S100 calcium binding protein A14
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
STAR steroidogenic acute regulatory protein
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
TACSTD2 tumor-associated calcium signal transducer 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSC22D3 TSC22 domain family, member 3
TTC39A tetratricopeptide repeat domain 39A
TUBA1A tubulin, alpha 1a
TUBB2A tubulin, beta 2A class IIa
TXNIP thioredoxin interacting protein
UGDH UDP-glucose 6-dehydrogenase
XIST X inactive specific transcript (non-protein coding)
ZMYND8 zinc finger, MYND-type containing 8

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
BARD1 BRCA1 associated RING domain 1
CALD1 caldesmon 1
CCDC85B coiled-coil domain containing 85B
CCND1 cyclin D1
CDC25A cell division cycle 25A
CDC45 cell division cycle 45
CDC6 cell division cycle 6
CDCA4 cell division cycle associated 4
CDK1 cyclin-dependent kinase 1
CNPY3 canopy FGF signaling regulator 3
COL4A1 collagen, type IV, alpha 1
CTPS1 CTP synthase 1
CXCL2 chemokine (C-X-C motif) ligand 2
CYR61 cysteine-rich, angiogenic inducer, 61
DHFR dihydrofolate reductase
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EPHB2 EPH receptor B2
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP7 fatty acid binding protein 7, brain
FEN1 flap structure-specific endonuclease 1
FOSL1 FOS-like antigen 1
GADD45B growth arrest and DNA-damage-inducible, beta
GINS2 GINS complex subunit 2 (Psf2 homolog)
HADH hydroxyacyl-CoA dehydrogenase
HDAC9 histone deacetylase 9
IFITM1 interferon induced transmembrane protein 1
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL13RA2 interleukin 13 receptor, alpha 2
ITM2A integral membrane protein 2A
MAP2K6 mitogen-activated protein kinase kinase 6
MCAM melanoma cell adhesion molecule
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MYL9 myosin, light chain 9, regulatory
NDRG2 NDRG family member 2
OLFML3 olfactomedin-like 3
PCNA proliferating cell nuclear antigen
PHGDH phosphoglycerate dehydrogenase
PLK1 polo-like kinase 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PROM1 prominin 1
PRSS23 protease, serine, 23
RAD51 RAD51 recombinase
RFC2 replication factor C (activator 1) 2, 40kDa
RFC3 replication factor C (activator 1) 3, 38kDa
RFC4 replication factor C (activator 1) 4, 37kDa
RGS2 regulator of G-protein signaling 2
RNASEH2A ribonuclease H2, subunit A
SHQ1 SHQ1, H/ACA ribonucleoprotein assembly factor
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SNRPD1 small nuclear ribonucleoprotein D1 polypeptide 16kDa
SRSF3 serine/arginine-rich splicing factor 3
SRSF7 serine/arginine-rich splicing factor 7
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
TMEM97 transmembrane protein 97
TPM1 tropomyosin 1 (alpha)
TRIP13 thyroid hormone receptor interactor 13
USP1 ubiquitin specific peptidase 1
VRK1 vaccinia related kinase 1
ZWINT ZW10 interacting kinetochore protein