BRD-A70155556_NP-001236_A549_6.0_h_40.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

58 genes differentially expressed following the BRD-A70155556_NP-001236_A549_6.0_h_40.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANK2 ankyrin 2, neuronal
AQP1 aquaporin 1 (Colton blood group)
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD24 CD24 molecule
CLEC2B C-type lectin domain family 2, member B
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
DCLK1 doublecortin-like kinase 1
DCN decorin
DDIT4 DNA-damage-inducible transcript 4
EFS embryonal Fyn-associated substrate
GPM6B glycoprotein M6B
GREM1 gremlin 1, DAN family BMP antagonist
GSTA1 glutathione S-transferase alpha 1
HDDC2 HD domain containing 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
JUN jun proto-oncogene
MAN1A1 mannosidase, alpha, class 1A, member 1
MMP12 matrix metallopeptidase 12
NUPR1 nuclear protein, transcriptional regulator, 1
OSBPL10 oxysterol binding protein-like 10
P2RY14 purinergic receptor P2Y, G-protein coupled, 14
PERP PERP, TP53 apoptosis effector
PLAGL1 pleiomorphic adenoma gene-like 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAP1GAP RAP1 GTPase activating protein
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SFN stratifin
SNAI2 snail family zinc finger 2
SPARCL1 SPARC-like 1 (hevin)
TGFBR3 transforming growth factor, beta receptor III
TRIB3 tribbles pseudokinase 3
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
CAST calpastatin
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CD14 CD14 molecule
CDCA4 cell division cycle associated 4
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CLEC11A C-type lectin domain family 11, member A
DKK1 dickkopf WNT signaling pathway inhibitor 1
GADD45B growth arrest and DNA-damage-inducible, beta
IRS2 insulin receptor substrate 2
ITM2C integral membrane protein 2C
LOXL2 lysyl oxidase-like 2
LTBP3 latent transforming growth factor beta binding protein 3
LYPD1 LY6/PLAUR domain containing 1
MYBPC1 myosin binding protein C, slow type
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PLAUR plasminogen activator, urokinase receptor
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RPL37A ribosomal protein L37a
SORL1 sortilin-related receptor, L(DLR class) A repeats containing