BRD-A68739437_NPK76-II-72-1_MCF7_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

62 genes differentially expressed following the BRD-A68739437_NPK76-II-72-1_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARG2 arginase 2
BLNK B-cell linker
CCL5 chemokine (C-C motif) ligand 5
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CP ceruloplasmin (ferroxidase)
CRELD2 cysteine-rich with EGF-like domains 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GADD45A growth arrest and DNA-damage-inducible, alpha
GDF15 growth differentiation factor 15
GPX3 glutathione peroxidase 3
HIST1H2BG histone cluster 1, H2bg
HOXB2 homeobox B2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
NNMT nicotinamide N-methyltransferase
PLIN2 perilipin 2
PXMP2 peroxisomal membrane protein 2, 22kDa
RTN1 reticulon 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
TARP TCR gamma alternate reading frame protein
VDAC1 voltage-dependent anion channel 1
YME1L1 YME1-like 1 ATPase

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ACKR3 atypical chemokine receptor 3
AHR aryl hydrocarbon receptor
AKR1C3 aldo-keto reductase family 1, member C3
ALCAM activated leukocyte cell adhesion molecule
ARHGAP32 Rho GTPase activating protein 32
CADM1 cell adhesion molecule 1
CLU clusterin
CST3 cystatin C
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CYB5R2 cytochrome b5 reductase 2
DMD dystrophin
DSP desmoplakin
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FBN2 fibrillin 2
GPX2 glutathione peroxidase 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IGFBP4 insulin-like growth factor binding protein 4
KRT14 keratin 14, type I
NPDC1 neural proliferation, differentiation and control, 1
NRCAM neuronal cell adhesion molecule
PBK PDZ binding kinase
RBP1 retinol binding protein 1, cellular
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOSTDC1 sclerostin domain containing 1
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TNS3 tensin 3
TP53 tumor protein p53
TP63 tumor protein p63
TPD52L1 tumor protein D52-like 1
WFDC2 WAP four-disulfide core domain 2