BRD-A68739437_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

85 genes differentially expressed following the BRD-A68739437_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C4BPA complement component 4 binding protein, alpha
CLTC clathrin, heavy chain (Hc)
CSRP1 cysteine and glycine-rich protein 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASN fatty acid synthase
GPX3 glutathione peroxidase 3
GRAMD3 GRAM domain containing 3
GSTA4 glutathione S-transferase alpha 4
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MELK maternal embryonic leucine zipper kinase
MFAP5 microfibrillar associated protein 5
MSMO1 methylsterol monooxygenase 1
NDRG2 NDRG family member 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
PER2 period circadian clock 2
PER3 period circadian clock 3
PHACTR2 phosphatase and actin regulator 2
PTN pleiotrophin
RGS1 regulator of G-protein signaling 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCRG1 stimulator of chondrogenesis 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SIK1 salt-inducible kinase 1

decreased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANXA3 annexin A3
BCL2A1 BCL2-related protein A1
C5AR1 complement component 5a receptor 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CD9 CD9 molecule
CHL1 cell adhesion molecule L1-like
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CRIP1 cysteine-rich protein 1 (intestinal)
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
DKK1 dickkopf WNT signaling pathway inhibitor 1
ERAP2 endoplasmic reticulum aminopeptidase 2
FAS Fas cell surface death receptor
FOSL1 FOS-like antigen 1
FPGS folylpolyglutamate synthase
FPR1 formyl peptide receptor 1
GCA grancalcin, EF-hand calcium binding protein
HEBP1 heme binding protein 1
KRT5 keratin 5, type II
LPAR1 lysophosphatidic acid receptor 1
LYZ lysozyme
MAP2K3 mitogen-activated protein kinase kinase 3
MDK midkine (neurite growth-promoting factor 2)
MMP9 matrix metallopeptidase 9
MNDA myeloid cell nuclear differentiation antigen
MSX1 msh homeobox 1
MX1 MX dynamin-like GTPase 1
NFIB nuclear factor I/B
OLFM4 olfactomedin 4
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLIN3 perilipin 3
PLK2 polo-like kinase 2
POSTN periostin, osteoblast specific factor
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRR7 proline rich 7 (synaptic)
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RCAN1 regulator of calcineurin 1
S100A12 S100 calcium binding protein A12
S100A8 S100 calcium binding protein A8
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC35F2 solute carrier family 35, member F2
SNX10 sorting nexin 10
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TLR1 toll-like receptor 1
TLR4 toll-like receptor 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
VCAN versican