BRD-A67552655_oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, ethyl ester- [cas]_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-A67552655_oxiranecarboxylic acid, 2-[6-(4-chlorophenoxy)hexyl]-, ethyl ester- [cas]_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADD3 adducin 3 (gamma)
ATF3 activating transcription factor 3
AZIN1 antizyme inhibitor 1
CAST calpastatin
CHN1 chimerin 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXADR coxsackie virus and adenovirus receptor
DENND2D DENN/MADD domain containing 2D
DPT dermatopontin
EMP1 epithelial membrane protein 1
FCGBP Fc fragment of IgG binding protein
FGFR2 fibroblast growth factor receptor 2
H1F0 H1 histone family, member 0
HSPA2 heat shock 70kDa protein 2
KCTD12 potassium channel tetramerization domain containing 12
MMD monocyte to macrophage differentiation-associated
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP19 matrix metallopeptidase 19
MUC16 mucin 16, cell surface associated
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PRSS21 protease, serine, 21 (testisin)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SGCE sarcoglycan, epsilon
SPAG16 sperm associated antigen 16
SRPX2 sushi-repeat containing protein, X-linked 2
TCTN1 tectonic family member 1
TUBB2A tubulin, beta 2A class IIa

decreased expression

Symbol Name
AKAP8 A kinase (PRKA) anchor protein 8
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EGR2 early growth response 2
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GULP1 GULP, engulfment adaptor PTB domain containing 1
HDDC2 HD domain containing 2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
LUM lumican
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MRPS2 mitochondrial ribosomal protein S2
MSN moesin
NEFH neurofilament, heavy polypeptide
PLK2 polo-like kinase 2
PROM1 prominin 1
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
STOM stomatin
TARP TCR gamma alternate reading frame protein
TGM2 transglutaminase 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a