BRD-A63667919_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-A63667919_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
BEX4 brain expressed, X-linked 4
CD200 CD200 molecule
CD36 CD36 molecule (thrombospondin receptor)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CES1 carboxylesterase 1
CFB complement factor B
CFD complement factor D (adipsin)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL1A2 collagen, type I, alpha 2
COL5A2 collagen, type V, alpha 2
CPE carboxypeptidase E
CPM carboxypeptidase M
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSNK2A2 casein kinase 2, alpha prime polypeptide
CYBRD1 cytochrome b reductase 1
DEPTOR DEP domain containing MTOR-interacting protein
DFNA5 deafness, autosomal dominant 5
EML3 echinoderm microtubule associated protein like 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
F13A1 coagulation factor XIII, A1 polypeptide
FAM129A family with sequence similarity 129, member A
FAXDC2 fatty acid hydroxylase domain containing 2
G0S2 G0/G1 switch 2
GMPR guanosine monophosphate reductase
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXB2 homeobox B2
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFBP5 insulin-like growth factor binding protein 5
IL1R1 interleukin 1 receptor, type I
KCTD14 potassium channel tetramerization domain containing 14
LEF1 lymphoid enhancer-binding factor 1
LGALS8 lectin, galactoside-binding, soluble, 8
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MN1 meningioma (disrupted in balanced translocation) 1
MYOF myoferlin
NR4A2 nuclear receptor subfamily 4, group A, member 2
PDE4A phosphodiesterase 4A, cAMP-specific
PDGFC platelet derived growth factor C
POSTN periostin, osteoblast specific factor
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SULF1 sulfatase 1
TMC5 transmembrane channel-like 5
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIB2 tribbles pseudokinase 2
VCAN versican
VTCN1 V-set domain containing T cell activation inhibitor 1
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
C8ORF4 chromosome 8 open reading frame 4
CD24 CD24 molecule
CLU clusterin
CXADR coxsackie virus and adenovirus receptor
CXCL14 chemokine (C-X-C motif) ligand 14
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
EIF5A eukaryotic translation initiation factor 5A
MAB21L2 mab-21-like 2 (C. elegans)
PALLD palladin, cytoskeletal associated protein
PLK1 polo-like kinase 1
RABAC1 Rab acceptor 1 (prenylated)
STOM stomatin
TM4SF1 transmembrane 4 L six family member 1
TMED9 transmembrane emp24 protein transport domain containing 9
XBP1 X-box binding protein 1