BRD-A63646118_Fumonisin B1_SW948_6.0_h_151.2_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

76 genes differentially expressed following the BRD-A63646118_Fumonisin B1_SW948_6.0_h_151.2_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPTL2 angiopoietin-like 2
AQP1 aquaporin 1 (Colton blood group)
ASPN asporin
BGN biglycan
CA2 carbonic anhydrase II
CA4 carbonic anhydrase IV
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD93 CD93 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
COL5A2 collagen, type V, alpha 2
CTSK cathepsin K
CXCL10 chemokine (C-X-C motif) ligand 10
DCN decorin
DKK3 dickkopf WNT signaling pathway inhibitor 3
FAM107A family with sequence similarity 107, member A
FAP fibroblast activation protein, alpha
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FHL1 four and a half LIM domains 1
GPNMB glycoprotein (transmembrane) nmb
GREM1 gremlin 1, DAN family BMP antagonist
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IL13RA1 interleukin 13 receptor, alpha 1
LDOC1 leucine zipper, down-regulated in cancer 1
LUM lumican
MEF2C myocyte enhancer factor 2C
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MKNK1 MAP kinase interacting serine/threonine kinase 1
MSMB microseminoprotein, beta-
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1X metallothionein 1X
MXRA5 matrix-remodelling associated 5
MZB1 marginal zone B and B1 cell-specific protein
NREP neuronal regeneration related protein
POSTN periostin, osteoblast specific factor
PXDN peroxidasin
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFTN1 raftlin, lipid raft linker 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SULF1 sulfatase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THBS2 thrombospondin 2
TMEM30B transmembrane protein 30B
TNNT1 troponin T type 1 (skeletal, slow)
XPO7 exportin 7

decreased expression

Symbol Name
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ADGRG2 adhesion G protein-coupled receptor G2
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
CLU clusterin
DUSP5 dual specificity phosphatase 5
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FOLR1 folate receptor 1 (adult)
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LY75 lymphocyte antigen 75
MARCKS myristoylated alanine-rich protein kinase C substrate
NUP98 nucleoporin 98kDa
PLA2G16 phospholipase A2, group XVI
PROM1 prominin 1
RBMS1 RNA binding motif, single stranded interacting protein 1
SLPI secretory leukocyte peptidase inhibitor
SRSF6 serine/arginine-rich splicing factor 6
TAC1 tachykinin, precursor 1
TM4SF1 transmembrane 4 L six family member 1
TSC22D1 TSC22 domain family, member 1
UBE2S ubiquitin-conjugating enzyme E2S
VCAM1 vascular cell adhesion molecule 1