BRD-A62057054_MDL 11,939_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

17 genes differentially expressed following the BRD-A62057054_MDL 11,939_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
HOOK2 hook microtubule-tethering protein 2
HSPA2 heat shock 70kDa protein 2
KIAA1598
KLK11 kallikrein-related peptidase 11
LYN LYN proto-oncogene, Src family tyrosine kinase
PLEKHJ1 pleckstrin homology domain containing, family J member 1
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
C6ORF62 chromosome 6 open reading frame 62
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
GPM6B glycoprotein M6B
PLP1 proteolipid protein 1
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
STOM stomatin
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)