BRD-A60245366_AS-601245_SKBR3_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

128 genes differentially expressed following the BRD-A60245366_AS-601245_SKBR3_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BTG3 BTG family, member 3
CCL20 chemokine (C-C motif) ligand 20
CDC42 cell division cycle 42
CERS6 ceramide synthase 6
CLDN10 claudin 10
CTTN cortactin
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL8 chemokine (C-X-C motif) ligand 8
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
HOPX HOP homeobox
IFRD2 interferon-related developmental regulator 2
ITM2A integral membrane protein 2A
ITM2C integral membrane protein 2C
LAPTM4B lysosomal protein transmembrane 4 beta
LCN2 lipocalin 2
LTA4H leukotriene A4 hydrolase
LYPD1 LY6/PLAUR domain containing 1
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MEIS1 Meis homeobox 1
MN1 meningioma (disrupted in balanced translocation) 1
OSBPL10 oxysterol binding protein-like 10
P3H2 prolyl 3-hydroxylase 2
PLBD1 phospholipase B domain containing 1
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme
QPCT glutaminyl-peptide cyclotransferase
RSRP1 arginine/serine-rich protein 1
SIK1 salt-inducible kinase 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SORT1 sortilin 1
SPON1 spondin 1, extracellular matrix protein
STXBP2 syntaxin binding protein 2
TIMP3 TIMP metallopeptidase inhibitor 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNNC1 troponin C type 1 (slow)
TNNC2 troponin C type 2 (fast)
TSPAN13 tetraspanin 13
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1

decreased expression

Symbol Name
ADIRF adipogenesis regulatory factor
ADM adrenomedullin
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ARID4B AT rich interactive domain 4B (RBP1-like)
ASF1A anti-silencing function 1A histone chaperone
AURKA aurora kinase A
BAMBI BMP and activin membrane-bound inhibitor
BASP1 brain abundant, membrane attached signal protein 1
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BLCAP bladder cancer associated protein
BTG1 B-cell translocation gene 1, anti-proliferative
CCND1 cyclin D1
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHD7 chromodomain helicase DNA binding protein 7
CHSY1 chondroitin sulfate synthase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL15A1 collagen, type XV, alpha 1
CRABP2 cellular retinoic acid binding protein 2
CXCL12 chemokine (C-X-C motif) ligand 12
DEFB1 defensin, beta 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EGR2 early growth response 2
FAS Fas cell surface death receptor
GABPB1 GA binding protein transcription factor, beta subunit 1
GSPT2 G1 to S phase transition 2
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IGFBP5 insulin-like growth factor binding protein 5
IGFBP6 insulin-like growth factor binding protein 6
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
JMJD6 jumonji domain containing 6
KIAA0355 KIAA0355
KLHL9 kelch-like family member 9
KRT14 keratin 14, type I
KRT15 keratin 15, type I
MARCKS myristoylated alanine-rich protein kinase C substrate
MCL1 myeloid cell leukemia 1
MID1IP1 MID1 interacting protein 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NET1 neuroepithelial cell transforming 1
NRBF2 nuclear receptor binding factor 2
NRN1 neuritin 1
NUP62 nucleoporin 62kDa
OPN3 opsin 3
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDLIM5 PDZ and LIM domain 5
PLK1 polo-like kinase 1
RAB31 RAB31, member RAS oncogene family
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RPP38 ribonuclease P/MRP 38kDa subunit
SCGB2A2 secretoglobin, family 2A, member 2
SEPHS1 selenophosphate synthetase 1
SFRP1 secreted frizzled-related protein 1
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SNAP25 synaptosomal-associated protein, 25kDa
SOX4 SRY (sex determining region Y)-box 4
SPP1 secreted phosphoprotein 1
TBC1D31 TBC1 domain family, member 31
TBPL1 TBP-like 1
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGIF1 TGFB-induced factor homeobox 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TP53 tumor protein p53
USP6NL USP6 N-terminal like
VCAN versican
WAC WW domain containing adaptor with coiled-coil
WEE1 WEE1 G2 checkpoint kinase
XBP1 X-box binding protein 1
ZHX2 zinc fingers and homeoboxes 2
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF217 zinc finger protein 217
ZNF22 zinc finger protein 22