BRD-A60245366_AS-601245_BT20_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

105 genes differentially expressed following the BRD-A60245366_AS-601245_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
AQP9 aquaporin 9
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ARPP21 cAMP-regulated phosphoprotein, 21kDa
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
CCL20 chemokine (C-C motif) ligand 20
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
COL3A1 collagen, type III, alpha 1
CST7 cystatin F (leukocystatin)
CTSZ cathepsin Z
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP2 dual specificity phosphatase 2
EGR1 early growth response 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EREG epiregulin
FASTKD5 FAST kinase domains 5
FKBP11 FK506 binding protein 11, 19 kDa
FKBP1A FK506 binding protein 1A, 12kDa
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45A growth arrest and DNA-damage-inducible, alpha
GPNMB glycoprotein (transmembrane) nmb
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUK1 guanylate kinase 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HP haptoglobin
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
IFI30 interferon, gamma-inducible protein 30
IFITM3 interferon induced transmembrane protein 3
IGKV4-1 immunoglobulin kappa variable 4-1
IL1RN interleukin 1 receptor antagonist
LYZ lysozyme
MBP myelin basic protein
MXI1 MAX interactor 1, dimerization protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
PLK2 polo-like kinase 2
PLVAP plasmalemma vesicle associated protein
PRNP prion protein
PRR7 proline rich 7 (synaptic)
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
REEP5 receptor accessory protein 5
S100A2 S100 calcium binding protein A2
SDC2 syndecan 2
SEPP1 selenoprotein P, plasma, 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPON2 spondin 2, extracellular matrix protein
TCF4 transcription factor 4
THBS1 thrombospondin 1
THY1 Thy-1 cell surface antigen
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TRAC T cell receptor alpha constant
TRD T cell receptor delta locus
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADGRG6 adhesion G protein-coupled receptor G6
ADIRF adipogenesis regulatory factor
AMIGO2 adhesion molecule with Ig-like domain 2
CAPN6 calpain 6
CAST calpastatin
CD24 CD24 molecule
CDC25B cell division cycle 25B
DLK1 delta-like 1 homolog (Drosophila)
DMD dystrophin
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ERBB2 erb-b2 receptor tyrosine kinase 2
GSTP1 glutathione S-transferase pi 1
IGFBP6 insulin-like growth factor binding protein 6
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MAPK13 mitogen-activated protein kinase 13
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NMI N-myc (and STAT) interactor
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRN1 neuritin 1
NT5E 5'-nucleotidase, ecto (CD73)
PCYOX1L prenylcysteine oxidase 1 like
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SFRP1 secreted frizzled-related protein 1
SGCE sarcoglycan, epsilon
SORBS3 sorbin and SH3 domain containing 3
SOX4 SRY (sex determining region Y)-box 4
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPTBN1 spectrin, beta, non-erythrocytic 1
SRPX sushi-repeat containing protein, X-linked
TNS3 tensin 3
TP53 tumor protein p53
TPD52L1 tumor protein D52-like 1
TRIM16 tripartite motif containing 16
ZDHHC13 zinc finger, DHHC-type containing 13
ZNF185 zinc finger protein 185 (LIM domain)