BRD-A58767537_afatinib_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

37 genes differentially expressed following the BRD-A58767537_afatinib_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
C10ORF10 chromosome 10 open reading frame 10
CD163 CD163 molecule
GPX3 glutathione peroxidase 3
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
MMP3 matrix metallopeptidase 3
POLG2 polymerase (DNA directed), gamma 2, accessory subunit

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG2 BTG family, member 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
DUSP4 dual specificity phosphatase 4
EGR3 early growth response 3
EPHA2 EPH receptor A2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAS Fas cell surface death receptor
FGF13 fibroblast growth factor 13
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GPM6B glycoprotein M6B
GPRC5A G protein-coupled receptor, class C, group 5, member A
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IGFBP3 insulin-like growth factor binding protein 3
JAG1 jagged 1
LIF leukemia inhibitory factor
MME membrane metallo-endopeptidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEFH neurofilament, heavy polypeptide
PER2 period circadian clock 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
RCAN1 regulator of calcineurin 1
SELENBP1 selenium binding protein 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SNAP25 synaptosomal-associated protein, 25kDa
TMSB15A thymosin beta 15a
ZFP36 ZFP36 ring finger protein