BRD-A57957888_N-Acetyl-DL-homocysteine Thiolactone_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

80 genes differentially expressed following the BRD-A57957888_N-Acetyl-DL-homocysteine Thiolactone_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ACKR3 atypical chemokine receptor 3
AUTS2 autism susceptibility candidate 2
BPHL biphenyl hydrolase-like (serine hydrolase)
C5ORF28 chromosome 5 open reading frame 28
CPE carboxypeptidase E
DAAM1 dishevelled associated activator of morphogenesis 1
FGL2 fibrinogen-like 2
FOLR1 folate receptor 1 (adult)
GBP1 guanylate binding protein 1, interferon-inducible
GCLC glutamate-cysteine ligase, catalytic subunit
GPX2 glutathione peroxidase 2
GRIA2 glutamate receptor, ionotropic, AMPA 2
GTPBP8 GTP-binding protein 8 (putative)
KCTD12 potassium channel tetramerization domain containing 12
MARCH6 membrane-associated ring finger (C3HC4) 6, E3 ubiquitin protein ligase
MMP12 matrix metallopeptidase 12
MPPED2 metallophosphoesterase domain containing 2
NES nestin
NNT nicotinamide nucleotide transhydrogenase
PECAM1 platelet/endothelial cell adhesion molecule 1
PITX2 paired-like homeodomain 2
PLBD1 phospholipase B domain containing 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RGS5 regulator of G-protein signaling 5
SDC2 syndecan 2
SFRP1 secreted frizzled-related protein 1
SHOX2 short stature homeobox 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
ST18 suppression of tumorigenicity 18, zinc finger
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TFF1 trefoil factor 1
TMEM176B transmembrane protein 176B
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNIP1 TNFAIP3 interacting protein 1
TPBG trophoblast glycoprotein
VEGFA vascular endothelial growth factor A
WRB tryptophan rich basic protein
ZBTB20 zinc finger and BTB domain containing 20

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOD apolipoprotein D
BHLHE41 basic helix-loop-helix family, member e41
C1ORF115 chromosome 1 open reading frame 115
CHRDL1 chordin-like 1
CKS2 CDC28 protein kinase regulatory subunit 2
COL10A1 collagen, type X, alpha 1
CXADR coxsackie virus and adenovirus receptor
CXCL12 chemokine (C-X-C motif) ligand 12
DHCR24 24-dehydrocholesterol reductase
FOXO4 forkhead box O4
GHR growth hormone receptor
HOXC6 homeobox C6
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
IDI1 isopentenyl-diphosphate delta isomerase 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAOB monoamine oxidase B
PDGFC platelet derived growth factor C
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PLA2G16 phospholipase A2, group XVI
PLTP phospholipid transfer protein
PRKACB protein kinase, cAMP-dependent, catalytic, beta
PROS1 protein S (alpha)
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSPH phosphoserine phosphatase
QDPR quinoid dihydropteridine reductase
RPL38 ribosomal protein L38
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SQLE squalene epoxidase
SRPX sushi-repeat containing protein, X-linked
STXBP2 syntaxin binding protein 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TRIM14 tripartite motif containing 14
TXLNA taxilin alpha
WIPF2 WAS/WASL interacting protein family, member 2
YME1L1 YME1-like 1 ATPase