BRD-A56020723_CA-074-Me_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

42 genes differentially expressed following the BRD-A56020723_CA-074-Me_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CBR1 carbonyl reductase 1
CD36 CD36 molecule (thrombospondin receptor)
CES1 carboxylesterase 1
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4
IFRD1 interferon-related developmental regulator 1
IGKV4-1 immunoglobulin kappa variable 4-1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
OLFM1 olfactomedin 1
PFN2 profilin 2
PGD phosphogluconate dehydrogenase
PIR pirin (iron-binding nuclear protein)
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
CD81 CD81 molecule
EPHA3 EPH receptor A3
FBLN1 fibulin 1
HIST3H2A histone cluster 3, H2a
IFITM1 interferon induced transmembrane protein 1
IL13RA2 interleukin 13 receptor, alpha 2
KLK11 kallikrein-related peptidase 11
NDRG1 N-myc downstream regulated 1
NME4 NME/NM23 nucleoside diphosphate kinase 4
SLC39A4 solute carrier family 39 (zinc transporter), member 4
STC1 stanniocalcin 1
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TYMS thymidylate synthetase
VIM vimentin
ZBTB18 zinc finger and BTB domain containing 18