BRD-A56020723_CA-074-Me_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-A56020723_CA-074-Me_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
BASP1 brain abundant, membrane attached signal protein 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JUN jun proto-oncogene
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
NDRG1 N-myc downstream regulated 1
NQO1 NAD(P)H dehydrogenase, quinone 1
PCOLCE2 procollagen C-endopeptidase enhancer 2
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLPI secretory leukocyte peptidase inhibitor

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AMOTL2 angiomotin like 2
CNN3 calponin 3, acidic
COL5A2 collagen, type V, alpha 2
CTGF connective tissue growth factor
CTSH cathepsin H
EFHD1 EF-hand domain family, member D1
KRT19 keratin 19, type I
METRN meteorin, glial cell differentiation regulator
NEFL neurofilament, light polypeptide
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NT5DC2 5'-nucleotidase domain containing 2
SOX4 SRY (sex determining region Y)-box 4
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TCF4 transcription factor 4
TRIM2 tripartite motif containing 2
VCAN versican