BRD-A56020723_CA-074-Me_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

27 genes differentially expressed following the BRD-A56020723_CA-074-Me_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ARG2 arginase 2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CA12 carbonic anhydrase XII
DAPK1 death-associated protein kinase 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
PROM1 prominin 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
TPD52L1 tumor protein D52-like 1
TSKU tsukushi, small leucine rich proteoglycan
UGDH UDP-glucose 6-dehydrogenase
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28

decreased expression

Symbol Name
CDC42 cell division cycle 42
COL4A5 collagen, type IV, alpha 5
EFNB2 ephrin-B2
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
NREP neuronal regeneration related protein
NT5DC2 5'-nucleotidase domain containing 2
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
SRSF6 serine/arginine-rich splicing factor 6