BRD-A56020723_CA-074-Me_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-A56020723_CA-074-Me_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
CA12 carbonic anhydrase XII
CBR3 carbonyl reductase 3
CD93 CD93 molecule
CTSL cathepsin L
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HPSE heparanase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
MAP2 microtubule-associated protein 2
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NOTCH3 notch 3
NQO1 NAD(P)H dehydrogenase, quinone 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
PGD phosphogluconate dehydrogenase
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
RAP1GAP RAP1 GTPase activating protein
S100P S100 calcium binding protein P
SDC1 syndecan 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TALDO1 transaldolase 1
THBD thrombomodulin
TPM4 tropomyosin 4
TSPAN7 tetraspanin 7
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
UPP1 uridine phosphorylase 1

decreased expression

Symbol Name
CRIP1 cysteine-rich protein 1 (intestinal)
DMD dystrophin
IFITM3 interferon induced transmembrane protein 3
MAPT microtubule-associated protein tau
MTA1 metastasis associated 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TSPAN4 tetraspanin 4
TUBA1A tubulin, alpha 1a