BRD-A56020723_CA-074-Me_HT29_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

160 genes differentially expressed following the BRD-A56020723_CA-074-Me_HT29_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD2 abhydrolase domain containing 2
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
ADM adrenomedullin
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
ASPH aspartate beta-hydroxylase
ASPN asporin
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
BAG2 BCL2-associated athanogene 2
BCL6 B-cell CLL/lymphoma 6
C20ORF24 chromosome 20 open reading frame 24
C3 complement component 3
CA12 carbonic anhydrase XII
CASP7 caspase 7, apoptosis-related cysteine peptidase
CBR3 carbonyl reductase 3
CDA cytidine deaminase
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLU clusterin
COL15A1 collagen, type XV, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSL cathepsin L
CXCL13 chemokine (C-X-C motif) ligand 13
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DEFB1 defensin, beta 1
DUSP5 dual specificity phosphatase 5
ELOVL5 ELOVL fatty acid elongase 5
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EREG epiregulin
FABP4 fatty acid binding protein 4, adipocyte
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
FOSL1 FOS-like antigen 1
FZD7 frizzled class receptor 7
G0S2 G0/G1 switch 2
G6PD glucose-6-phosphate dehydrogenase
GAA glucosidase, alpha; acid
GCLC glutamate-cysteine ligase, catalytic subunit
GCLM glutamate-cysteine ligase, modifier subunit
GEM GTP binding protein overexpressed in skeletal muscle
GHITM growth hormone inducible transmembrane protein
GJA1 gap junction protein, alpha 1, 43kDa
GPC1 glypican 1
GPI glucose-6-phosphate isomerase
GPX2 glutathione peroxidase 2
HDGFRP3 hepatoma-derived growth factor, related protein 3
HMOX1 heme oxygenase 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JARID2 jumonji, AT rich interactive domain 2
KYNU kynureninase
LMO2 LIM domain only 2 (rhombotin-like 1)
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1B microtubule-associated protein 1B
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MUC1 mucin 1, cell surface associated
NAMPT nicotinamide phosphoribosyltransferase
NKX3-1 NK3 homeobox 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NRIP3 nuclear receptor interacting protein 3
PCOLCE2 procollagen C-endopeptidase enhancer 2
PFN2 profilin 2
PGD phosphogluconate dehydrogenase
PIR pirin (iron-binding nuclear protein)
PLAUR plasminogen activator, urokinase receptor
PPAP2B phosphatidic acid phosphatase type 2B
PRCP prolylcarboxypeptidase (angiotensinase C)
PROCR protein C receptor, endothelial
PTGES prostaglandin E synthase
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RAP1GAP RAP1 GTPase activating protein
RHOB ras homolog family member B
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFN stratifin
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SORD sorbitol dehydrogenase
SPAG4 sperm associated antigen 4
SPARCL1 SPARC-like 1 (hevin)
SYNJ2 synaptojanin 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TNPO1 transportin 1
TRIM16 tripartite motif containing 16
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AIM1 absent in melanoma 1
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
AMIGO2 adhesion molecule with Ig-like domain 2
C4BPA complement component 4 binding protein, alpha
CCDC109B coiled-coil domain containing 109B
CCND2 cyclin D2
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDC25B cell division cycle 25B
CPM carboxypeptidase M
CRABP1 cellular retinoic acid binding protein 1
CXADR coxsackie virus and adenovirus receptor
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DENND2D DENN/MADD domain containing 2D
DKK3 dickkopf WNT signaling pathway inhibitor 3
DPP4 dipeptidyl-peptidase 4
ETV5 ets variant 5
FCGBP Fc fragment of IgG binding protein
GATA2 GATA binding protein 2
GIMAP5 GTPase, IMAP family member 5
HIST1H4C histone cluster 1, H4c
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL17RB interleukin 17 receptor B
KIF1BP KIF1 binding protein
LDOC1 leucine zipper, down-regulated in cancer 1
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LOXL1 lysyl oxidase-like 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MFAP5 microfibrillar associated protein 5
MME membrane metallo-endopeptidase
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NKX2-1 NK2 homeobox 1
NPDC1 neural proliferation, differentiation and control, 1
OLFM4 olfactomedin 4
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PEG10 paternally expressed 10
PRRX1 paired related homeobox 1
PRSS2 protease, serine, 2 (trypsin 2)
RECQL RecQ helicase-like
RGS2 regulator of G-protein signaling 2
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB1D2 secretoglobin, family 1D, member 2
SFRP1 secreted frizzled-related protein 1
STK26 serine/threonine protein kinase 26
TARP TCR gamma alternate reading frame protein
TCF21 transcription factor 21
TGFBR3 transforming growth factor, beta receptor III
TM4SF4 transmembrane 4 L six family member 4
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPSAB1 tryptase alpha/beta 1
TSPAN13 tetraspanin 13
TSPAN4 tetraspanin 4
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a
TXNIP thioredoxin interacting protein