BRD-A47714657_2-methoxy-5-((6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)phenol KCR-2_HA1E_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-A47714657_2-methoxy-5-((6-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)phenol KCR-2_HA1E_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARG1 arginase 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CST3 cystatin C
CXCL14 chemokine (C-X-C motif) ligand 14
FADS2 fatty acid desaturase 2
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GLUL glutamate-ammonia ligase
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
MNAT1 MNAT CDK-activating kinase assembly factor 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
S100P S100 calcium binding protein P
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKAP12 A kinase (PRKA) anchor protein 12
AREG amphiregulin
ASS1 argininosuccinate synthase 1
C1ORF116 chromosome 1 open reading frame 116
CD24 CD24 molecule
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CKB creatine kinase, brain
CREB1 cAMP responsive element binding protein 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DES desmin
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFS embryonal Fyn-associated substrate
EMP1 epithelial membrane protein 1
FHL1 four and a half LIM domains 1
FHOD3 formin homology 2 domain containing 3
FN1 fibronectin 1
FOLR1 folate receptor 1 (adult)
GAS1 growth arrest-specific 1
HES1 hes family bHLH transcription factor 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
KCNK3 potassium channel, two pore domain subfamily K, member 3
KRT13 keratin 13, type I
LAMP3 lysosomal-associated membrane protein 3
MAOB monoamine oxidase B
MIR22HG MIR22 host gene
MYBPC1 myosin binding protein C, slow type
NEB nebulin
NEFH neurofilament, heavy polypeptide
NPIPB3 nuclear pore complex interacting protein family, member B3
NR2F1 nuclear receptor subfamily 2, group F, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
PEG10 paternally expressed 10
PEG3 paternally expressed 3
PHACTR2 phosphatase and actin regulator 2
PPL periplakin
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RGCC regulator of cell cycle
RHOBTB3 Rho-related BTB domain containing 3
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERTAD2 SERTA domain containing 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SRPX sushi-repeat containing protein, X-linked
TACSTD2 tumor-associated calcium signal transducer 2
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TUBB6 tubulin, beta 6 class V
UBE2J1 ubiquitin-conjugating enzyme E2, J1
XIST X inactive specific transcript (non-protein coding)
ZBED2 zinc finger, BED-type containing 2