BRD-A45498368_WYE-125132_MDAMB231_24_h_0.12_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

98 genes differentially expressed following the BRD-A45498368_WYE-125132_MDAMB231_24_h_0.12_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
ANXA4 annexin A4
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CDC25B cell division cycle 25B
CHMP4A charged multivesicular body protein 4A
CST1 cystatin SN
CSTB cystatin B (stefin B)
DEPTOR DEP domain containing MTOR-interacting protein
DSP desmoplakin
FABP4 fatty acid binding protein 4, adipocyte
FXR1 fragile X mental retardation, autosomal homolog 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPNMB glycoprotein (transmembrane) nmb
GRN granulin
HBP1 HMG-box transcription factor 1
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IL1B interleukin 1, beta
INHBA inhibin, beta A
IRS2 insulin receptor substrate 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KRT19 keratin 19, type I
LAMC2 laminin, gamma 2
LDLR low density lipoprotein receptor
LPXN leupaxin
MAGED1 melanoma antigen family D1
MLPH melanophilin
MME membrane metallo-endopeptidase
MYC v-myc avian myelocytomatosis viral oncogene homolog
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PGLS 6-phosphogluconolactonase
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PPAP2B phosphatidic acid phosphatase type 2B
PROM1 prominin 1
PTX3 pentraxin 3, long
RALGDS ral guanine nucleotide dissociation stimulator
SDCBP syndecan binding protein (syntenin)
SEPP1 selenoprotein P, plasma, 1
SFN stratifin
SLC22A18 solute carrier family 22, member 18
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
TGIF1 TGFB-induced factor homeobox 1
TM4SF1 transmembrane 4 L six family member 1
TPP1 tripeptidyl peptidase I
TRIOBP TRIO and F-actin binding protein
TUBA1A tubulin, alpha 1a
WDTC1 WD and tetratricopeptide repeats 1

decreased expression

Symbol Name
ALG8 ALG8, alpha-1,3-glucosyltransferase
AQP3 aquaporin 3 (Gill blood group)
CA2 carbonic anhydrase II
CCNE1 cyclin E1
CD320 CD320 molecule
CDC25A cell division cycle 25A
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma
CENPU centromere protein U
COPS3 COP9 signalosome subunit 3
CPE carboxypeptidase E
CTPS1 CTP synthase 1
DDIT4 DNA-damage-inducible transcript 4
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EIF5A eukaryotic translation initiation factor 5A
ENPEP glutamyl aminopeptidase (aminopeptidase A)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FEN1 flap structure-specific endonuclease 1
GAL galanin/GMAP prepropeptide
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GINS1 GINS complex subunit 1 (Psf1 homolog)
GRIA2 glutamate receptor, ionotropic, AMPA 2
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ICMT isoprenylcysteine carboxyl methyltransferase
IGFBP3 insulin-like growth factor binding protein 3
KLF4 Kruppel-like factor 4 (gut)
LMNB1 lamin B1
MAP7 microtubule-associated protein 7
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
NUP210 nucleoporin 210kDa
PARP2 poly (ADP-ribose) polymerase 2
PBX1 pre-B-cell leukemia homeobox 1
PLBD1 phospholipase B domain containing 1
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRKCH protein kinase C, eta
RCAN2 regulator of calcineurin 2
S100A8 S100 calcium binding protein A8
SESN1 sestrin 1
SMC1A structural maintenance of chromosomes 1A
TDO2 tryptophan 2,3-dioxygenase
TMEM109 transmembrane protein 109
TMPO thymopoietin