BRD-A45498368_WYE-125132_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-A45498368_WYE-125132_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
AMIGO2 adhesion molecule with Ig-like domain 2
APOD apolipoprotein D
BIK BCL2-interacting killer (apoptosis-inducing)
BTG1 B-cell translocation gene 1, anti-proliferative
C10ORF10 chromosome 10 open reading frame 10
CAST calpastatin
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHIC2 cysteine-rich hydrophobic domain 2
COL10A1 collagen, type X, alpha 1
CTGF connective tissue growth factor
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FAM129A family with sequence similarity 129, member A
FCGBP Fc fragment of IgG binding protein
GCC2 GRIP and coiled-coil domain containing 2
GRB7 growth factor receptor-bound protein 7
HBP1 HMG-box transcription factor 1
HMGB2 high mobility group box 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ISG20 interferon stimulated exonuclease gene 20kDa
KDM3A lysine (K)-specific demethylase 3A
KLHL21 kelch-like family member 21
MAN1A1 mannosidase, alpha, class 1A, member 1
PDE4B phosphodiesterase 4B, cAMP-specific
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PXDN peroxidasin
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SFRP1 secreted frizzled-related protein 1
STOM stomatin
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)

decreased expression

Symbol Name
ACLY ATP citrate lyase
ADIRF adipogenesis regulatory factor
ADO 2-aminoethanethiol (cysteamine) dioxygenase
AMD1 adenosylmethionine decarboxylase 1
CCL19 chemokine (C-C motif) ligand 19
CDC25A cell division cycle 25A
CST7 cystatin F (leukocystatin)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FZD5 frizzled class receptor 5
GAB2 GRB2-associated binding protein 2
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HOXA10 homeobox A10
LAMP3 lysosomal-associated membrane protein 3
MNDA myeloid cell nuclear differentiation antigen
NPTX2 neuronal pentraxin II
PNN pinin, desmosome associated protein
S100A12 S100 calcium binding protein A12
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TMEM176B transmembrane protein 176B
TSPAN8 tetraspanin 8