BRD-A41451487_PK-11195_VCAP_24.0_h_160.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-A41451487_PK-11195_VCAP_24.0_h_160.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AIM1 absent in melanoma 1
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
CAT catalase
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CLDN3 claudin 3
EAPP E2F-associated phosphoprotein
FNBP1L formin binding protein 1-like
GCLC glutamate-cysteine ligase, catalytic subunit
GRB10 growth factor receptor-bound protein 10
HIST1H2AC histone cluster 1, H2ac
IGFBP3 insulin-like growth factor binding protein 3
INHBB inhibin, beta B
KRT18 keratin 18, type I
LGALS4 lectin, galactoside-binding, soluble, 4
MMP9 matrix metallopeptidase 9
MTSS1 metastasis suppressor 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PRKACB protein kinase, cAMP-dependent, catalytic, beta
SESN1 sestrin 1
SLC38A1 solute carrier family 38, member 1
SULF1 sulfatase 1
TGFB1 transforming growth factor, beta 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TPP1 tripeptidyl peptidase I

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AK2 adenylate kinase 2
APP amyloid beta (A4) precursor protein
CCNF cyclin F
CKAP4 cytoskeleton-associated protein 4
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
FAS Fas cell surface death receptor
FKBP10 FK506 binding protein 10, 65 kDa
FUS FUS RNA binding protein
KRT6B keratin 6B, type II
LMNB1 lamin B1
LMO4 LIM domain only 4
LTF lactotransferrin
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
TACSTD2 tumor-associated calcium signal transducer 2