BRD-A39996500_radicicol_MDAMB231_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

121 genes differentially expressed following the BRD-A39996500_radicicol_MDAMB231_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C3 aldo-keto reductase family 1, member C3
BAG3 BCL2-associated athanogene 3
CHMP6 charged multivesicular body protein 6
COLEC12 collectin sub-family member 12
COTL1 coactosin-like F-actin binding protein 1
CRABP1 cellular retinoic acid binding protein 1
CTSC cathepsin C
CXCL2 chemokine (C-X-C motif) ligand 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FGFR2 fibroblast growth factor receptor 2
GATA3 GATA binding protein 3
GUSBP11 glucuronidase, beta pseudogene 11
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMOX1 heme oxygenase 1
HOXB6 homeobox B6
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
HSPB1 heat shock 27kDa protein 1
HSPH1 heat shock 105kDa/110kDa protein 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI27 interferon, alpha-inducible protein 27
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
JCHAIN joining chain of multimeric IgA and IgM
MTSS1 metastasis suppressor 1
MTUS1 microtubule associated tumor suppressor 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NRCAM neuronal cell adhesion molecule
PBX3 pre-B-cell leukemia homeobox 3
QPRT quinolinate phosphoribosyltransferase
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
RPL38 ribosomal protein L38
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
STMN2 stathmin 2
SYNGR2 synaptogyrin 2
TBX3 T-box 3
TIMP3 TIMP metallopeptidase inhibitor 3
TSKU tsukushi, small leucine rich proteoglycan
TWIST1 twist family bHLH transcription factor 1
VCAM1 vascular cell adhesion molecule 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADRB2 adrenoceptor beta 2, surface
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD1E CD1e molecule
CD24 CD24 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CP ceruloplasmin (ferroxidase)
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DEPTOR DEP domain containing MTOR-interacting protein
DUSP6 dual specificity phosphatase 6
E2F2 E2F transcription factor 2
ELANE elastase, neutrophil expressed
EREG epiregulin
F3 coagulation factor III (thromboplastin, tissue factor)
FABP4 fatty acid binding protein 4, adipocyte
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAS Fas cell surface death receptor
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HES1 hes family bHLH transcription factor 1
HMGA2 high mobility group AT-hook 2
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER3 immediate early response 3
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
KLF10 Kruppel-like factor 10
LCN2 lipocalin 2
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP7 microtubule-associated protein 7
MARCKSL1 MARCKS-like 1
MET MET proto-oncogene, receptor tyrosine kinase
MPO myeloperoxidase
MYB v-myb avian myeloblastosis viral oncogene homolog
NOTCH2 notch 2
NPY neuropeptide Y
SCGB2A1 secretoglobin, family 2A, member 1
SCGB2A2 secretoglobin, family 2A, member 2
SERINC5 serine incorporator 5
SIRT3 sirtuin 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
VGLL4 vestigial-like family member 4
WEE1 WEE1 G2 checkpoint kinase
ZBTB18 zinc finger and BTB domain containing 18
ZFP36L2 ZFP36 ring finger protein-like 2