BRD-A39093044_2-[(chloroacetyl)(3-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-A39093044_2-[(chloroacetyl)(3-methoxyphenyl)amino]-N-(2-phenylethyl)-2-thien-2-ylacetamide_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CADM1 cell adhesion molecule 1
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CTH cystathionine gamma-lyase
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP5 dual specificity phosphatase 5
FOLR1 folate receptor 1 (adult)
GPX7 glutathione peroxidase 7
HMOX1 heme oxygenase 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
LRRC15 leucine rich repeat containing 15
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEFH neurofilament, heavy polypeptide
PIR pirin (iron-binding nuclear protein)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
SCRG1 stimulator of chondrogenesis 1
SFTPA2 surfactant protein A2

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ADAMDEC1 ADAM-like, decysin 1
CA2 carbonic anhydrase II
CDH3 cadherin 3, type 1, P-cadherin (placental)
CSTA cystatin A (stefin A)
CTSH cathepsin H
DLD dihydrolipoamide dehydrogenase
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
INSIG1 insulin induced gene 1
KRT14 keratin 14, type I
NR2F6 nuclear receptor subfamily 2, group F, member 6
PMM2 phosphomannomutase 2
PRAME preferentially expressed antigen in melanoma
PXDN peroxidasin
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK1 serum/glucocorticoid regulated kinase 1
SH3BGRL SH3 domain binding glutamate-rich protein like
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TFRC transferrin receptor