BRD-A37735495_2-[(chloroacetyl)(4-fluorophenyl)amino]-N-cyclohexyl-2-pyridin-3-ylacetamide_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

59 genes differentially expressed following the BRD-A37735495_2-[(chloroacetyl)(4-fluorophenyl)amino]-N-cyclohexyl-2-pyridin-3-ylacetamide_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
ANXA10 annexin A10
BHLHE40 basic helix-loop-helix family, member e40
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CSRP1 cysteine and glycine-rich protein 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FAM129A family with sequence similarity 129, member A
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IL6ST interleukin 6 signal transducer
INSIG1 insulin induced gene 1
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KRT23 keratin 23, type I
MEIS2 Meis homeobox 2
MSMO1 methylsterol monooxygenase 1
PLIN2 perilipin 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
STC2 stanniocalcin 2
STK10 serine/threonine kinase 10
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase
ZFP36 ZFP36 ring finger protein
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ACSL1 acyl-CoA synthetase long-chain family member 1
AGR2 anterior gradient 2
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
APOD apolipoprotein D
B3GNT1
BASP1 brain abundant, membrane attached signal protein 1
CYR61 cysteine-rich, angiogenic inducer, 61
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ERBB2 erb-b2 receptor tyrosine kinase 2
GLRX glutaredoxin (thioltransferase)
GRB14 growth factor receptor-bound protein 14
HOXB6 homeobox B6
KRT18 keratin 18, type I
LAMB1 laminin, beta 1
MAOA monoamine oxidase A
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
PSD3 pleckstrin and Sec7 domain containing 3
RGS13 regulator of G-protein signaling 13
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TNNC1 troponin C type 1 (slow)
TNNT1 troponin T type 1 (skeletal, slow)
TOP2A topoisomerase (DNA) II alpha 170kDa
TSC22D1 TSC22 domain family, member 1