BRD-A37704979_SB-203580_HT29_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

71 genes differentially expressed following the BRD-A37704979_SB-203580_HT29_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
BLNK B-cell linker
CADPS2 Ca++-dependent secretion activator 2
CAV2 caveolin 2
CCND1 cyclin D1
CD36 CD36 molecule (thrombospondin receptor)
CLC Charcot-Leyden crystal galectin
CLDN1 claudin 1
CXCL5 chemokine (C-X-C motif) ligand 5
DSP desmoplakin
GJA1 gap junction protein, alpha 1, 43kDa
GPATCH8 G patch domain containing 8
HBB hemoglobin, beta
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IFNAR1 interferon (alpha, beta and omega) receptor 1
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
INHBB inhibin, beta B
KDM5D lysine (K)-specific demethylase 5D
LEPR leptin receptor
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MDFIC MyoD family inhibitor domain containing
MECOM MDS1 and EVI1 complex locus
PBX1 pre-B-cell leukemia homeobox 1
PPAP2B phosphatidic acid phosphatase type 2B
RPS5 ribosomal protein S5
SCGB2A2 secretoglobin, family 2A, member 2
SST somatostatin
TGFBI transforming growth factor, beta-induced, 68kDa
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TWIST1 twist family bHLH transcription factor 1

decreased expression

Symbol Name
AQP3 aquaporin 3 (Gill blood group)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHIC2 cysteine-rich hydrophobic domain 2
CLDN3 claudin 3
CPM carboxypeptidase M
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EXOSC4 exosome component 4
F3 coagulation factor III (thromboplastin, tissue factor)
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HOPX HOP homeobox
INHBA inhibin, beta A
JCHAIN joining chain of multimeric IgA and IgM
KRT14 keratin 14, type I
LAPTM4B lysosomal protein transmembrane 4 beta
LDHB lactate dehydrogenase B
LMO3 LIM domain only 3 (rhombotin-like 2)
MB myoglobin
MGP matrix Gla protein
MXI1 MAX interactor 1, dimerization protein
MYLK myosin light chain kinase
NGRN neugrin, neurite outgrowth associated
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OXTR oxytocin receptor
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
POSTN periostin, osteoblast specific factor
PRSS3 protease, serine, 3
PRUNE2 prune homolog 2 (Drosophila)
PTPRC protein tyrosine phosphatase, receptor type, C
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLN sarcolipin
TMEM158 transmembrane protein 158 (gene/pseudogene)
TRBC1 T cell receptor beta constant 1
TUBA1A tubulin, alpha 1a
ZMAT3 zinc finger, matrin-type 3