BRD-A36630025_-666_RMGI_6.0_h_0.35_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

167 genes differentially expressed following the BRD-A36630025_-666_RMGI_6.0_h_0.35_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD6 abhydrolase domain containing 6
ADCY1 adenylate cyclase 1 (brain)
AIM1 absent in melanoma 1
ALB albumin
ALDOB aldolase B, fructose-bisphosphate
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ANPEP alanyl (membrane) aminopeptidase
APOC2 apolipoprotein C-II
ATF3 activating transcription factor 3
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX4 brain expressed, X-linked 4
BTG2 BTG family, member 2
CADPS2 Ca++-dependent secretion activator 2
CAV1 caveolin 1, caveolae protein, 22kDa
CCL4 chemokine (C-C motif) ligand 4
CCL8 chemokine (C-C motif) ligand 8
CCNA1 cyclin A1
CD40 CD40 molecule, TNF receptor superfamily member 5
CD52 CD52 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFB complement factor B
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL11A1 collagen, type XI, alpha 1
COL3A1 collagen, type III, alpha 1
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
CSTA cystatin A (stefin A)
CXADR coxsackie virus and adenovirus receptor
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL9 chemokine (C-X-C motif) ligand 9
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DSG2 desmoglein 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGF epidermal growth factor
EGR2 early growth response 2
EGR3 early growth response 3
EIF5A eukaryotic translation initiation factor 5A
FBP1 fructose-1,6-bisphosphatase 1
FLNA filamin A, alpha
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GAA glucosidase, alpha; acid
GADD45B growth arrest and DNA-damage-inducible, beta
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GNAS GNAS complex locus
GPNMB glycoprotein (transmembrane) nmb
GPR37 G protein-coupled receptor 37 (endothelin receptor type B-like)
GSDMB gasdermin B
GULP1 GULP, engulfment adaptor PTB domain containing 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HNMT histamine N-methyltransferase
IER5 immediate early response 5
IGFBP5 insulin-like growth factor binding protein 5
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KLF10 Kruppel-like factor 10
LAMP2 lysosomal-associated membrane protein 2
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
LY96 lymphocyte antigen 96
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MARCKSL1 MARCKS-like 1
MMP12 matrix metallopeptidase 12
MXRA5 matrix-remodelling associated 5
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUAK1 NUAK family, SNF1-like kinase, 1
OLFM4 olfactomedin 4
ORM1 orosomucoid 1
PAH phenylalanine hydroxylase
PBX3 pre-B-cell leukemia homeobox 3
PDE4B phosphodiesterase 4B, cAMP-specific
PDLIM3 PDZ and LIM domain 3
PEG10 paternally expressed 10
PIEZO1 piezo-type mechanosensitive ion channel component 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POSTN periostin, osteoblast specific factor
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SULF1 sulfatase 1
SYNM synemin, intermediate filament protein
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TF transferrin
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMSB15A thymosin beta 15a
TPP1 tripeptidyl peptidase I
TRPS1 trichorhinophalangeal syndrome I
XIST X inactive specific transcript (non-protein coding)
ZDHHC11 zinc finger, DHHC-type containing 11
ZFPM2 zinc finger protein, FOG family member 2
ZNF304 zinc finger protein 304
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACOT9 acyl-CoA thioesterase 9
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ASCC3 activating signal cointegrator 1 complex subunit 3
AUTS2 autism susceptibility candidate 2
BMP2 bone morphogenetic protein 2
CCNA2 cyclin A2
CDC20 cell division cycle 20
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CLIC4 chloride intracellular channel 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DERA deoxyribose-phosphate aldolase (putative)
EGFR epidermal growth factor receptor
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPS8 epidermal growth factor receptor pathway substrate 8
FBXO11 F-box protein 11
FCGBP Fc fragment of IgG binding protein
FOXJ3 forkhead box J3
FOXO1 forkhead box O1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
HMOX1 heme oxygenase 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGHD immunoglobulin heavy constant delta
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL6R interleukin 6 receptor
ITGA6 integrin, alpha 6
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JMJD6 jumonji domain containing 6
KDM5D lysine (K)-specific demethylase 5D
KLF6 Kruppel-like factor 6
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP5 lysosomal-associated membrane protein family, member 5
LSR lipolysis stimulated lipoprotein receptor
MAP7 microtubule-associated protein 7
MICALL1 MICAL-like 1
MMP10 matrix metallopeptidase 10
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYH10 myosin, heavy chain 10, non-muscle
MYO10 myosin X
OPTN optineurin
PAX8 paired box 8
PDHX pyruvate dehydrogenase complex, component X
PFKP phosphofructokinase, platelet
PRKCA protein kinase C, alpha
PWP1 PWP1 homolog (S. cerevisiae)
RBMS1 RNA binding motif, single stranded interacting protein 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLPI secretory leukocyte peptidase inhibitor
SMAD3 SMAD family member 3
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPTBN1 spectrin, beta, non-erythrocytic 1
TCF4 transcription factor 4
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TIMP3 TIMP metallopeptidase inhibitor 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLE4 transducin-like enhancer of split 4
TMEM100 transmembrane protein 100
TMEM47 transmembrane protein 47
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOP2A topoisomerase (DNA) II alpha 170kDa
VCAN versican