BRD-A35588707_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

157 genes differentially expressed following the BRD-A35588707_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AIF1 allograft inflammatory factor 1
ANPEP alanyl (membrane) aminopeptidase
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BAG3 BCL2-associated athanogene 3
BEX4 brain expressed, X-linked 4
BHLHE40 basic helix-loop-helix family, member e40
BHLHE41 basic helix-loop-helix family, member e41
BLCAP bladder cancer associated protein
BTG2 BTG family, member 2
C1ORF116 chromosome 1 open reading frame 116
C1ORF54 chromosome 1 open reading frame 54
C6ORF62 chromosome 6 open reading frame 62
CADM1 cell adhesion molecule 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCL5 chemokine (C-C motif) ligand 5
CCNG2 cyclin G2
CD24 CD24 molecule
CD46 CD46 molecule, complement regulatory protein
CD93 CD93 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLGN calmegin
COL1A1 collagen, type I, alpha 1
COL4A2 collagen, type IV, alpha 2
CSTA cystatin A (stefin A)
CTSZ cathepsin Z
CXCL13 chemokine (C-X-C motif) ligand 13
DDB2 damage-specific DNA binding protein 2, 48kDa
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP14 dual specificity phosphatase 14
EFNB2 ephrin-B2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FAM134A family with sequence similarity 134, member A
FBP1 fructose-1,6-bisphosphatase 1
FDXR ferredoxin reductase
FN1 fibronectin 1
GADD45A growth arrest and DNA-damage-inducible, alpha
IGF1 insulin-like growth factor 1 (somatomedin C)
INHBB inhibin, beta B
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT14 keratin 14, type I
KRT17 keratin 17, type I
LBH limb bud and heart development
LRP10 low density lipoprotein receptor-related protein 10
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MICALL1 MICAL-like 1
MMP12 matrix metallopeptidase 12
MSMB microseminoprotein, beta-
NKX3-1 NK3 homeobox 1
NNMT nicotinamide N-methyltransferase
PINK1 PTEN induced putative kinase 1
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPL periplakin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PSAP prosaposin
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTHLH parathyroid hormone-like hormone
S100A2 S100 calcium binding protein A2
SAP18 Sin3A-associated protein, 18kDa
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SESN1 sestrin 1
SFN stratifin
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC46A3 solute carrier family 46, member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SNAI2 snail family zinc finger 2
SQRDL sulfide quinone reductase-like (yeast)
TDO2 tryptophan 2,3-dioxygenase
TGM2 transglutaminase 2
THBS1 thrombospondin 1
TIGAR TP53 induced glycolysis regulatory phosphatase
TRIM22 tripartite motif containing 22
TRIM38 tripartite motif containing 38
TWF2 twinfilin actin binding protein 2
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADAM10 ADAM metallopeptidase domain 10
AFP alpha-fetoprotein
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AURKA aurora kinase A
BMPR1A bone morphogenetic protein receptor, type IA
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNA2 cyclin A2
CCNB2 cyclin B2
CHL1 cell adhesion molecule L1-like
CLIC4 chloride intracellular channel 4
CRIP1 cysteine-rich protein 1 (intestinal)
CXCL14 chemokine (C-X-C motif) ligand 14
DCK deoxycytidine kinase
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DLC1 DLC1 Rho GTPase activating protein
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
DMD dystrophin
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
F3 coagulation factor III (thromboplastin, tissue factor)
FOXJ3 forkhead box J3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GPC3 glypican 3
GRIA2 glutamate receptor, ionotropic, AMPA 2
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITGA6 integrin, alpha 6
KLF6 Kruppel-like factor 6
LCN2 lipocalin 2
LIMS1 LIM and senescent cell antigen-like domains 1
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAP7 microtubule-associated protein 7
MBNL1 muscleblind-like splicing regulator 1
MELK maternal embryonic leucine zipper kinase
MUC16 mucin 16, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
PAM peptidylglycine alpha-amidating monooxygenase
PBK PDZ binding kinase
PLK1 polo-like kinase 1
PRC1 protein regulator of cytokinesis 1
PRSS2 protease, serine, 2 (trypsin 2)
PSD3 pleckstrin and Sec7 domain containing 3
PTCH1 patched 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
QKI QKI, KH domain containing, RNA binding
RHOBTB3 Rho-related BTB domain containing 3
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RUFY3 RUN and FYVE domain containing 3
S100P S100 calcium binding protein P
SATB2 SATB homeobox 2
SIK1 salt-inducible kinase 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SPINK1 serine peptidase inhibitor, Kazal type 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TBC1D4 TBC1 domain family, member 4
TCF12 transcription factor 12
TCF4 transcription factor 4
TFF3 trefoil factor 3 (intestinal)
TGFBR3 transforming growth factor, beta receptor III
TNC tenascin C
TOP2A topoisomerase (DNA) II alpha 170kDa
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TXN thioredoxin
UBE2C ubiquitin-conjugating enzyme E2C
USP3 ubiquitin specific peptidase 3
VCAM1 vascular cell adhesion molecule 1