BRD-A31107743_89671_EFO27_6.0_h_0.09_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

136 genes differentially expressed following the BRD-A31107743_89671_EFO27_6.0_h_0.09_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACBD3 acyl-CoA binding domain containing 3
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
C6ORF62 chromosome 6 open reading frame 62
CALU calumenin
CCL20 chemokine (C-C motif) ligand 20
CDC42 cell division cycle 42
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CKAP4 cytoskeleton-associated protein 4
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
CREB3L2 cAMP responsive element binding protein 3-like 2
CRLF1 cytokine receptor-like factor 1
CRYAB crystallin, alpha B
CTGF connective tissue growth factor
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DFNA5 deafness, autosomal dominant 5
DLC1 DLC1 Rho GTPase activating protein
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSP desmoplakin
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
EREG epiregulin
F3 coagulation factor III (thromboplastin, tissue factor)
FKBP14 FK506 binding protein 14, 22 kDa
GARS glycyl-tRNA synthetase
GOLT1B golgi transport 1B
GUSBP11 glucuronidase, beta pseudogene 11
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIPK1 homeodomain interacting protein kinase 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLL1 immunoglobulin lambda-like polypeptide 1
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IGLV2-23 immunoglobulin lambda variable 2-23
JCHAIN joining chain of multimeric IgA and IgM
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KRT4 keratin 4, type II
LCN2 lipocalin 2
LIF leukemia inhibitory factor
LTF lactotransferrin
MAGED1 melanoma antigen family D1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MATN2 matrilin 2
MB myoglobin
MUC4 mucin 4, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYLK myosin light chain kinase
NR1D2 nuclear receptor subfamily 1, group D, member 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PI3 peptidase inhibitor 3, skin-derived
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PPL periplakin
PSPH phosphoserine phosphatase
PTX3 pentraxin 3, long
RRBP1 ribosome binding protein 1
S100A2 S100 calcium binding protein A2
SEC31A SEC31 homolog A (S. cerevisiae)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPB surfactant protein B
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOX9 SRY (sex determining region Y)-box 9
SPRR2B small proline-rich protein 2B
SPRR3 small proline-rich protein 3
TBL2 transducin (beta)-like 2
THBS2 thrombospondin 2
TMED2 transmembrane emp24 domain trafficking protein 2
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TUFT1 tuftelin 1
XBP1 X-box binding protein 1
XIST X inactive specific transcript (non-protein coding)
ZIC1 Zic family member 1

decreased expression

Symbol Name
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8
BAD BCL2-associated agonist of cell death
BASP1 brain abundant, membrane attached signal protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCBL2 cysteine conjugate-beta lyase 2
CD1E CD1e molecule
CD36 CD36 molecule (thrombospondin receptor)
CD8A CD8a molecule
CLIC4 chloride intracellular channel 4
CXCL12 chemokine (C-X-C motif) ligand 12
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EFNB2 ephrin-B2
EID1 EP300 interacting inhibitor of differentiation 1
ENDOD1 endonuclease domain containing 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EXOSC4 exosome component 4
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FBXO21 F-box protein 21
FLNB filamin B, beta
FOS FBJ murine osteosarcoma viral oncogene homolog
GSTA4 glutathione S-transferase alpha 4
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ISOC1 isochorismatase domain containing 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
LDHB lactate dehydrogenase B
LOC100505650 uncharacterized LOC100505650
MAOA monoamine oxidase A
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP7 microtubule-associated protein 7
MRPS16 mitochondrial ribosomal protein S16
NET1 neuroepithelial cell transforming 1
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NPTX2 neuronal pentraxin II
NPY1R neuropeptide Y receptor Y1
PRKD3 protein kinase D3
PTGER4 prostaglandin E receptor 4 (subtype EP4)
QPCT glutaminyl-peptide cyclotransferase
RPS4Y1 ribosomal protein S4, Y-linked 1
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SRSF7 serine/arginine-rich splicing factor 7
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa