BRD-A30437061_-666_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-A30437061_-666_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIRF adipogenesis regulatory factor
AQP1 aquaporin 1 (Colton blood group)
CAV1 caveolin 1, caveolae protein, 22kDa
CCL4 chemokine (C-C motif) ligand 4
CCR1 chemokine (C-C motif) receptor 1
CD52 CD52 molecule
COL3A1 collagen, type III, alpha 1
CPM carboxypeptidase M
CXCL10 chemokine (C-X-C motif) ligand 10
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EVI2A ecotropic viral integration site 2A
FHOD3 formin homology 2 domain containing 3
FOXF1 forkhead box F1
G0S2 G0/G1 switch 2
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HOXB6 homeobox B6
HOXB7 homeobox B7
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFITM1 interferon induced transmembrane protein 1
IL7R interleukin 7 receptor
ISG15 ISG15 ubiquitin-like modifier
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD5 potassium channel tetramerization domain containing 5
LGALS3 lectin, galactoside-binding, soluble, 3
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MN1 meningioma (disrupted in balanced translocation) 1
MSN moesin
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PGK1 phosphoglycerate kinase 1
PMP22 peripheral myelin protein 22
SCUBE2 signal peptide, CUB domain, EGF-like 2
SFN stratifin
SMYD3 SET and MYND domain containing 3
WFDC2 WAP four-disulfide core domain 2
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CCNA2 cyclin A2
CXADR coxsackie virus and adenovirus receptor
DHRS2 dehydrogenase/reductase (SDR family) member 2
DLK1 delta-like 1 homolog (Drosophila)
DNM1L dynamin 1-like
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
GNAS GNAS complex locus
GUSBP11 glucuronidase, beta pseudogene 11
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDI1 isopentenyl-diphosphate delta isomerase 1
IFNGR1 interferon gamma receptor 1
IGHD immunoglobulin heavy constant delta
IGKC immunoglobulin kappa constant
IGLJ3 immunoglobulin lambda joining 3
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV2-23 immunoglobulin lambda variable 2-23
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
ITGA6 integrin, alpha 6
JCHAIN joining chain of multimeric IgA and IgM
JMJD6 jumonji domain containing 6
KIAA0368 KIAA0368
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
PLK2 polo-like kinase 2
PNN pinin, desmosome associated protein
PRPF4 pre-mRNA processing factor 4
PTP4A1 protein tyrosine phosphatase type IVA, member 1
S100P S100 calcium binding protein P
TBP TATA box binding protein
USP1 ubiquitin specific peptidase 1
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
YBX3 Y box binding protein 3