BRD-A29901043_KIN001-127_HCC515_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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64 genes differentially expressed following the BRD-A29901043_KIN001-127_HCC515_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
AGR2 anterior gradient 2
ALCAM activated leukocyte cell adhesion molecule
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD9 CD9 molecule
CD93 CD93 molecule
CLDN10 claudin 10
CPT1A carnitine palmitoyltransferase 1A (liver)
DEFB1 defensin, beta 1
DUOX2 dual oxidase 2
EHD3 EH-domain containing 3
HIST1H2BK histone cluster 1, H2bk
KRT13 keratin 13, type I
LDLR low density lipoprotein receptor
LMO2 LIM domain only 2 (rhombotin-like 1)
LTBP1 latent transforming growth factor beta binding protein 1
LY75 lymphocyte antigen 75
MAPT microtubule-associated protein tau
NELL2 NEL-like 2 (chicken)
NPEPL1 aminopeptidase-like 1
PBX1 pre-B-cell leukemia homeobox 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLAC8 placenta-specific 8
PTGES prostaglandin E synthase
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TSPAN8 tetraspanin 8
ZNF185 zinc finger protein 185 (LIM domain)

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
CALML5 calmodulin-like 5
CBS cystathionine-beta-synthase
CDC42 cell division cycle 42
CNN3 calponin 3, acidic
COL1A2 collagen, type I, alpha 2
COL3A1 collagen, type III, alpha 1
CP ceruloplasmin (ferroxidase)
DCT dopachrome tautomerase
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EIF5 eukaryotic translation initiation factor 5
EIF5A eukaryotic translation initiation factor 5A
FABP7 fatty acid binding protein 7, brain
FXYD6 FXYD domain containing ion transport regulator 6
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GINS1 GINS complex subunit 1 (Psf1 homolog)
H2AFZ H2A histone family, member Z
IFI27 interferon, alpha-inducible protein 27
IL1R2 interleukin 1 receptor, type II
KRT14 keratin 14, type I
KRT23 keratin 23, type I
NET1 neuroepithelial cell transforming 1
PAGE4 P antigen family, member 4 (prostate associated)
PELI1 pellino E3 ubiquitin protein ligase 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PSRC1 proline/serine-rich coiled-coil 1
RAD21 RAD21 homolog (S. pombe)
RND3 Rho family GTPase 3
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SNAI2 snail family zinc finger 2
TYRP1 tyrosinase-related protein 1
VEGFA vascular endothelial growth factor A