BRD-A22713669_BVT 948_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-A22713669_BVT 948_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANKRD10 ankyrin repeat domain 10
ATF3 activating transcription factor 3
C5AR1 complement component 5a receptor 1
CCL2 chemokine (C-C motif) ligand 2
CHN1 chimerin 1
COL11A1 collagen, type XI, alpha 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
DUSP10 dual specificity phosphatase 10
DUSP3 dual specificity phosphatase 3
ENC1 ectodermal-neural cortex 1 (with BTB domain)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO3 forkhead box O3
GADD45B growth arrest and DNA-damage-inducible, beta
HMOX1 heme oxygenase 1
INSIG1 insulin induced gene 1
JUN jun proto-oncogene
JUND jun D proto-oncogene
KLF6 Kruppel-like factor 6
LDLR low density lipoprotein receptor
LDOC1 leucine zipper, down-regulated in cancer 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K3 mitogen-activated protein kinase kinase 3
MLF1 myeloid leukemia factor 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
ODC1 ornithine decarboxylase 1
PDE4B phosphodiesterase 4B, cAMP-specific
PLAU plasminogen activator, urokinase
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
S100A8 S100 calcium binding protein A8
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TUBB2A tubulin, beta 2A class IIa
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VGLL1 vestigial-like family member 1
VWA5A von Willebrand factor A domain containing 5A
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ADA adenosine deaminase
ARMCX2 armadillo repeat containing, X-linked 2
ARMT1 acidic residue methyltransferase 1
B3GNT1
CBR3 carbonyl reductase 3
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CTSH cathepsin H
DACT1 dishevelled-binding antagonist of beta-catenin 1
EGR2 early growth response 2
ESR1 estrogen receptor 1
HEBP1 heme binding protein 1
IGF1R insulin-like growth factor 1 receptor
JAG1 jagged 1
LGALS8 lectin, galactoside-binding, soluble, 8
LY96 lymphocyte antigen 96
MATN2 matrilin 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH10 myosin, heavy chain 10, non-muscle
RPS11 ribosomal protein S11
TRIB1 tribbles pseudokinase 1
TXNDC9 thioredoxin domain containing 9
TYRP1 tyrosinase-related protein 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17