BRD-A22713669_BVT 948_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-A22713669_BVT 948_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
BTG2 BTG family, member 2
CAST calpastatin
CBS cystathionine-beta-synthase
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO3 forkhead box O3
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
JUN jun proto-oncogene
KLF6 Kruppel-like factor 6
KLF7 Kruppel-like factor 7 (ubiquitous)
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MKNK2 MAP kinase interacting serine/threonine kinase 2
N4BP2L2 NEDD4 binding protein 2-like 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PLIN2 perilipin 2
QPCT glutaminyl-peptide cyclotransferase
RAP1GAP RAP1 GTPase activating protein
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGCC regulator of cell cycle
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SQSTM1 sequestosome 1
TES testin LIM domain protein
TRIB3 tribbles pseudokinase 3
TSKU tsukushi, small leucine rich proteoglycan
TXNRD1 thioredoxin reductase 1
UPP1 uridine phosphorylase 1
VAT1 vesicle amine transport 1
VEGFA vascular endothelial growth factor A
WARS tryptophanyl-tRNA synthetase
ZFAND5 zinc finger, AN1-type domain 5
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
BASP1 brain abundant, membrane attached signal protein 1
BIRC5 baculoviral IAP repeat containing 5
CD36 CD36 molecule (thrombospondin receptor)
CHRDL1 chordin-like 1
CP ceruloplasmin (ferroxidase)
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DLGAP5 discs, large (Drosophila) homolog-associated protein 5
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM46A family with sequence similarity 46, member A
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GPX3 glutathione peroxidase 3
HEBP1 heme binding protein 1
HSPB8 heat shock 22kDa protein 8
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRF8 interferon regulatory factor 8
KIF20A kinesin family member 20A
LTF lactotransferrin
MAP7 microtubule-associated protein 7
MPC2 mitochondrial pyruvate carrier 2
NME4 NME/NM23 nucleoside diphosphate kinase 4
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SCGB2A2 secretoglobin, family 2A, member 2
SDC2 syndecan 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SLC44A4 solute carrier family 44, member 4
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SPON1 spondin 1, extracellular matrix protein
STMN1 stathmin 1
SUB1 SUB1 homolog (S. cerevisiae)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10