BRD-A18725729_2-[(chloroacetyl)(4-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

25 genes differentially expressed following the BRD-A18725729_2-[(chloroacetyl)(4-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDOB aldolase B, fructose-bisphosphate
CXCL2 chemokine (C-X-C motif) ligand 2
HMOX1 heme oxygenase 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
LTF lactotransferrin
MMP9 matrix metallopeptidase 9
OLFM4 olfactomedin 4
PAWR PRKC, apoptosis, WT1, regulator
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
STC2 stanniocalcin 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
ZBTB18 zinc finger and BTB domain containing 18
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
CLEC2B C-type lectin domain family 2, member B
DPYSL2 dihydropyrimidinase-like 2
MAP7 microtubule-associated protein 7
PPAP2B phosphatidic acid phosphatase type 2B
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A4 S100 calcium binding protein A4
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
SVIL supervillin
WWTR1 WW domain containing transcription regulator 1