BRD-A18411371_2-[(chloroacetyl)(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

53 genes differentially expressed following the BRD-A18411371_2-[(chloroacetyl)(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BTG1 B-cell translocation gene 1, anti-proliferative
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CHI3L2 chitinase 3-like 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDF15 growth differentiation factor 15
GPNMB glycoprotein (transmembrane) nmb
HSPA1A heat shock 70kDa protein 1A
IGFBP3 insulin-like growth factor binding protein 3
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16
NQO1 NAD(P)H dehydrogenase, quinone 1
PAWR PRKC, apoptosis, WT1, regulator
SEPP1 selenoprotein P, plasma, 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SQSTM1 sequestosome 1
STC1 stanniocalcin 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
CD36 CD36 molecule (thrombospondin receptor)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLEC2B C-type lectin domain family 2, member B
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COL5A1 collagen, type V, alpha 1
EIF5A eukaryotic translation initiation factor 5A
ENC1 ectodermal-neural cortex 1 (with BTB domain)
ETV1 ets variant 1
F2RL1 coagulation factor II (thrombin) receptor-like 1
FSD1 fibronectin type III and SPRY domain containing 1
HIST1H4C histone cluster 1, H4c
IGFBP6 insulin-like growth factor binding protein 6
LUM lumican
MCL1 myeloid cell leukemia 1
MFAP2 microfibrillar-associated protein 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PMP22 peripheral myelin protein 22
RGS2 regulator of G-protein signaling 2
S100A4 S100 calcium binding protein A4
SHB Src homology 2 domain containing adaptor protein B
SPON1 spondin 1, extracellular matrix protein
SST somatostatin
STIP1 stress-induced phosphoprotein 1
TGFB1 transforming growth factor, beta 1
THBS2 thrombospondin 2
TNNT1 troponin T type 1 (skeletal, slow)
VCAN versican
WFDC2 WAP four-disulfide core domain 2
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZBED2 zinc finger, BED-type containing 2