BRD-A18411371_2-[(chloroacetyl)(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-A18411371_2-[(chloroacetyl)(3-chlorophenyl)amino]-N-cyclohexyl-2-(4-methoxyphenyl)acetamide_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADM adrenomedullin
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5 arachidonate 5-lipoxygenase
ASNS asparagine synthetase (glutamine-hydrolyzing)
CALML4 calmodulin-like 4
CHN1 chimerin 1
CLGN calmegin
COL11A1 collagen, type XI, alpha 1
CX3CR1 chemokine (C-X3-C motif) receptor 1
DDIT4 DNA-damage-inducible transcript 4
DOK5 docking protein 5
EPS8 epidermal growth factor receptor pathway substrate 8
GADD45B growth arrest and DNA-damage-inducible, beta
GBE1 glucan (1,4-alpha-), branching enzyme 1
GCLM glutamate-cysteine ligase, modifier subunit
GSDMB gasdermin B
HBB hemoglobin, beta
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IGFBP5 insulin-like growth factor binding protein 5
KIAA0226L KIAA0226-like
LCN2 lipocalin 2
LEF1 lymphoid enhancer-binding factor 1
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MAP1B microtubule-associated protein 1B
MFAP5 microfibrillar associated protein 5
MKNK1 MAP kinase interacting serine/threonine kinase 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NQO1 NAD(P)H dehydrogenase, quinone 1
NT5E 5'-nucleotidase, ecto (CD73)
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SCG5 secretogranin V
SULF1 sulfatase 1
TRIM2 tripartite motif containing 2
TXNL4B thioredoxin-like 4B
VEGFA vascular endothelial growth factor A
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AQP3 aquaporin 3 (Gill blood group)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
KRT14 keratin 14, type I
LPL lipoprotein lipase
MAP7 microtubule-associated protein 7
PDZD2 PDZ domain containing 2
POSTN periostin, osteoblast specific factor
RRBP1 ribosome binding protein 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SESN1 sestrin 1
SFN stratifin
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SRPX sushi-repeat containing protein, X-linked
TCTA T-cell leukemia translocation altered
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
WWTR1 WW domain containing transcription regulator 1