BRD-A15297126_FLUOCINONIDE_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

88 genes differentially expressed following the BRD-A15297126_FLUOCINONIDE_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
CA12 carbonic anhydrase XII
CAPN2 calpain 2, (m/II) large subunit
CCND2 cyclin D2
CHL1 cell adhesion molecule L1-like
COL18A1 collagen, type XVIII, alpha 1
COL5A1 collagen, type V, alpha 1
CPD carboxypeptidase D
DDIT4 DNA-damage-inducible transcript 4
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP1 epithelial membrane protein 1
F13A1 coagulation factor XIII, A1 polypeptide
GPI glucose-6-phosphate isomerase
GSTA4 glutathione S-transferase alpha 4
HIPK2 homeodomain interacting protein kinase 2
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IGFBP4 insulin-like growth factor binding protein 4
IGFBP5 insulin-like growth factor binding protein 5
IRF7 interferon regulatory factor 7
JADE2 jade family PHD finger 2
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KDM5D lysine (K)-specific demethylase 5D
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP1B microtubule-associated protein 1B
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
PCOLCE procollagen C-endopeptidase enhancer
PGAM1 phosphoglycerate mutase 1 (brain)
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
RAB2A RAB2A, member RAS oncogene family
SEPP1 selenoprotein P, plasma, 1
SIRT3 sirtuin 3
SYBU syntabulin (syntaxin-interacting)
TNC tenascin C
TSC22D3 TSC22 domain family, member 3
TUBB2A tubulin, beta 2A class IIa
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
AEBP1 AE binding protein 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA4 annexin A4
ATF3 activating transcription factor 3
CASP6 caspase 6, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CHIC2 cysteine-rich hydrophobic domain 2
CRABP2 cellular retinoic acid binding protein 2
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15
EDN1 endothelin 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EXT1 exostosin glycosyltransferase 1
FILIP1L filamin A interacting protein 1-like
FST follistatin
GATA6 GATA binding protein 6
HIST1H1C histone cluster 1, H1c
HIST1H2BG histone cluster 1, H2bg
HIST1H4C histone cluster 1, H4c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
IGL immunoglobulin lambda locus
LRMP lymphoid-restricted membrane protein
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MEIS2 Meis homeobox 2
MSLN mesothelin
NXN nucleoredoxin
P3H2 prolyl 3-hydroxylase 2
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PDZD2 PDZ domain containing 2
PELI1 pellino E3 ubiquitin protein ligase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PTPRK protein tyrosine phosphatase, receptor type, K
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RGS5 regulator of G-protein signaling 5
S100A8 S100 calcium binding protein A8
SCGB2A1 secretoglobin, family 2A, member 1
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TCTA T-cell leukemia translocation altered
THBS1 thrombospondin 1
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
VAMP8 vesicle-associated membrane protein 8
XIST X inactive specific transcript (non-protein coding)