BRD-A13195221_11-(4-Diethylamino-phenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]dia_SW948_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-A13195221_11-(4-Diethylamino-phenyl)-3-phenyl-2,3,4,5,10,11-hexahydro-dibenzo[b,e][1,4]dia_SW948_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANGPTL2 angiopoietin-like 2
ATF3 activating transcription factor 3
CCND2 cyclin D2
CD163 CD163 molecule
CD86 CD86 molecule
CD9 CD9 molecule
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHN1 chimerin 1
COL5A2 collagen, type V, alpha 2
COL6A3 collagen, type VI, alpha 3
CRABP2 cellular retinoic acid binding protein 2
CTSK cathepsin K
CXADR coxsackie virus and adenovirus receptor
EMP1 epithelial membrane protein 1
FAM107A family with sequence similarity 107, member A
FST follistatin
GLUL glutamate-ammonia ligase
GREM1 gremlin 1, DAN family BMP antagonist
IGFBP5 insulin-like growth factor binding protein 5
IGFBP7 insulin-like growth factor binding protein 7
IGHM immunoglobulin heavy constant mu
IL13RA1 interleukin 13 receptor, alpha 1
JUP junction plakoglobin
KLF9 Kruppel-like factor 9
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LINC00341 long intergenic non-protein coding RNA 341
LRRC15 leucine rich repeat containing 15
MMP12 matrix metallopeptidase 12
MMP9 matrix metallopeptidase 9
MXRA5 matrix-remodelling associated 5
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OLFM1 olfactomedin 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PEG10 paternally expressed 10
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
POSTN periostin, osteoblast specific factor
PTN pleiotrophin
PXDN peroxidasin
RAB25 RAB25, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SNAI2 snail family zinc finger 2
SULF1 sulfatase 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TIMP2 TIMP metallopeptidase inhibitor 2
TPSAB1 tryptase alpha/beta 1
VSIG4 V-set and immunoglobulin domain containing 4
XIST X inactive specific transcript (non-protein coding)
ZMIZ1 zinc finger, MIZ-type containing 1
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
FABP7 fatty acid binding protein 7, brain
LAMP1 lysosomal-associated membrane protein 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MET MET proto-oncogene, receptor tyrosine kinase
MMP7 matrix metallopeptidase 7
MSX1 msh homeobox 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PSAP prosaposin
RPL27A ribosomal protein L27a
RPL36 ribosomal protein L36
RPL38 ribosomal protein L38
RPS4Y1 ribosomal protein S4, Y-linked 1
SLC52A2 solute carrier family 52 (riboflavin transporter), member 2
SRSF5 serine/arginine-rich splicing factor 5
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TSPAN8 tetraspanin 8
U2AF1 U2 small nuclear RNA auxiliary factor 1
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)